AF-399/41418395 structure

AF-399/41418395

TL;DR: AF-399/41418395 (CAS 496777-31-2) is a chemical compound with molecular formula C21H26N2O6S2 and molecular weight 466.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

ethyl 2-[(2-methoxy-5-pyrrolidin-1-ylsulfonylbenzoyl)amino]-4,5-dimethylthiophene-3-carboxylate

Also Known As: AF-399/41418395, ethyl 2-(2-methoxy-5-(pyrrolidin-1-ylsulfonyl)benzamido)-4,5-dimethylthiophene-3-carboxylate, F1227-0063, ETHYL 2-[2-METHOXY-5-(PYRROLIDINE-1-SULFONYL)BENZAMIDO]-4,5-DIMETHYLTHIOPHENE-3-CARBOXYLATE, ethyl 2-[(2-methoxy-5-pyrrolidin-1-ylsulfonylbenzoyl)amino]-4,5-dimethylthiophene-3-carboxylate

CAS: 496777-31-2
Molecular Formula C21H26N2O6S2
Molecular Weight 466.12 g/mol
LogP 3.58704
Topological Polar Surface Area 102.01 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 7
Rotatable Bonds 7
Exact Mass 466.12323
Heavy Atoms 31
Complexity 1101.3135

Chemical Identifiers

CAS Number 496777-31-2
SMILES CCOC(=O)C1=C(SC(=C1C)C)NC(=O)C2=C(C=CC(=C2)S(=O)(=O)N3CCCC3)OC

Product Overview

AF-399/41418395 (CAS 496777-31-2), with molecular formula C21H26N2O6S2 and molecular weight 466.12 g/mol. IUPAC: ethyl 2-[(2-methoxy-5-pyrrolidin-1-ylsulfonylbenzoyl)amino]-4,5-dimethylthiophene-3-carboxylate.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of AF-399/41418395

XLogP
3.58704
TPSA (Topological Polar Surface Area)
102.01
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
7
Rotatable Bonds
7
Heavy Atoms
31
Complexity
1101.3135
Exact Mass
466.12323
Monoisotopic Mass
466.12323
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of AF-399/41418395

The XLogP value of 3.58704 indicates that AF-399/41418395 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 102.01 Ų falls within the moderate polarity range, balancing permeability and solubility for AF-399/41418395. Following Lipinski's Rule of Five, AF-399/41418395 has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of AF-399/41418395?

The CAS number of AF-399/41418395 is 496777-31-2.

What is the molecular formula of AF-399/41418395?

The molecular formula of AF-399/41418395 is C21H26N2O6S2.

What is the molecular weight of AF-399/41418395?

The molecular weight of AF-399/41418395 is 466.12 g/mol.

Where can I buy AF-399/41418395?

You can request a quote for AF-399/41418395 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for AF-399/41418395?

Yes, KEHONG BIO provides custom synthesis services for AF-399/41418395 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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