![(5Z)-5-(4-ethoxybenzylidene)-2-[4-(2-hydroxyethyl)piperazin-1-yl]-1,3-thiazol-4(5H)-one structure](/static/products/496/496772-86-2.png)
(5Z)-5-(4-ethoxybenzylidene)-2-[4-(2-hydroxyethyl)piperazin-1-yl]-1,3-thiazol-4(5H)-one
TL;DR: (5Z)-5-(4-ethoxybenzylidene)-2-[4-(2-hydroxyethyl)piperazin-1-yl]-1,3-thiazol-4(5H)-one (CAS 496772-86-2) is a chemical compound with molecular formula C18H23N3O3S and molecular weight 361.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5Z)-5-[(4-ethoxyphenyl)methylidene]-2-[4-(2-hydroxyethyl)piperazin-1-yl]-1,3-thiazol-4-one
Also Known As: (5Z)-5-(4-ethoxybenzylidene)-2-[4-(2-hydroxyethyl)piperazin-1-yl]-1,3-thiazol-4(5H)-one, (Z)-5-(4-ethoxybenzylidene)-2-(4-(2-hydroxyethyl)piperazin-1-yl)thiazol-4(5H)-one, 5-[(4-ethoxyphenyl)methylidene]-2-[4-(2-hydroxyethyl)piperazin-1-yl]-1,3-thiazol-4-one, (5Z)-5-[(4-ethoxyphenyl)methylidene]-2-[4-(2-hydroxyethyl)piperazin-1-yl]-1,3-thiazol-4-one
| Molecular Formula | C18H23N3O3S |
|---|---|
| Molecular Weight | 361.15 g/mol |
| LogP | 1.6655 |
| Topological Polar Surface Area | 65.37 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 5 |
| Exact Mass | 361.14603 |
| Heavy Atoms | 25 |
| Complexity | 664.6488 |
Chemical Identifiers
| CAS Number | 496772-86-2 |
|---|---|
| SMILES | CCOC1=CC=C(C=C1)/C=C\2/C(=O)N=C(S2)N3CCN(CC3)CCO |
Product Overview
(5Z)-5-(4-ethoxybenzylidene)-2-[4-(2-hydroxyethyl)piperazin-1-yl]-1,3-thiazol-4(5H)-one (CAS 496772-86-2), with molecular formula C18H23N3O3S and molecular weight 361.15 g/mol. IUPAC: (5Z)-5-[(4-ethoxyphenyl)methylidene]-2-[4-(2-hydroxyethyl)piperazin-1-yl]-1,3-thiazol-4-one.
Chemical Property Profile of (5Z)-5-(4-ethoxybenzylidene)-2-[4-(2-hydroxyethyl)piperazin-1-yl]-1,3-thiazol-4(5H)-one
Property Insights of (5Z)-5-(4-ethoxybenzylidene)-2-[4-(2-hydroxyethyl)piperazin-1-yl]-1,3-thiazol-4(5H)-one
The XLogP value of 1.6655 suggests moderate lipophilicity, balancing water solubility and membrane permeability for (5Z)-5-(4-ethoxybenzylidene)-2-[4-(2-hydroxyethyl)piperazin-1-yl]-1,3-thiazol-4(5H)-one. The TPSA of 65.37 Ų falls within the moderate polarity range, balancing permeability and solubility for (5Z)-5-(4-ethoxybenzylidene)-2-[4-(2-hydroxyethyl)piperazin-1-yl]-1,3-thiazol-4(5H)-one. Following Lipinski's Rule of Five, (5Z)-5-(4-ethoxybenzylidene)-2-[4-(2-hydroxyethyl)piperazin-1-yl]-1,3-thiazol-4(5H)-one has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (5Z)-5-(4-ethoxybenzylidene)-2-[4-(2-hydroxyethyl)piperazin-1-yl]-1,3-thiazol-4(5H)-one?
The CAS number of (5Z)-5-(4-ethoxybenzylidene)-2-[4-(2-hydroxyethyl)piperazin-1-yl]-1,3-thiazol-4(5H)-one is 496772-86-2.
What is the molecular formula of (5Z)-5-(4-ethoxybenzylidene)-2-[4-(2-hydroxyethyl)piperazin-1-yl]-1,3-thiazol-4(5H)-one?
The molecular formula of (5Z)-5-(4-ethoxybenzylidene)-2-[4-(2-hydroxyethyl)piperazin-1-yl]-1,3-thiazol-4(5H)-one is C18H23N3O3S.
What is the molecular weight of (5Z)-5-(4-ethoxybenzylidene)-2-[4-(2-hydroxyethyl)piperazin-1-yl]-1,3-thiazol-4(5H)-one?
The molecular weight of (5Z)-5-(4-ethoxybenzylidene)-2-[4-(2-hydroxyethyl)piperazin-1-yl]-1,3-thiazol-4(5H)-one is 361.15 g/mol.
Where can I buy (5Z)-5-(4-ethoxybenzylidene)-2-[4-(2-hydroxyethyl)piperazin-1-yl]-1,3-thiazol-4(5H)-one?
You can request a quote for (5Z)-5-(4-ethoxybenzylidene)-2-[4-(2-hydroxyethyl)piperazin-1-yl]-1,3-thiazol-4(5H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (5Z)-5-(4-ethoxybenzylidene)-2-[4-(2-hydroxyethyl)piperazin-1-yl]-1,3-thiazol-4(5H)-one?
Yes, KEHONG BIO provides custom synthesis services for (5Z)-5-(4-ethoxybenzylidene)-2-[4-(2-hydroxyethyl)piperazin-1-yl]-1,3-thiazol-4(5H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.