![(2E)-N-(5-{4-[(difluoromethyl)sulfanyl]benzyl}-1,3-thiazol-2-yl)-3-(furan-2-yl)prop-2-enamide structure](/static/products/496/496771-31-4.png)
(2E)-N-(5-{4-[(difluoromethyl)sulfanyl]benzyl}-1,3-thiazol-2-yl)-3-(furan-2-yl)prop-2-enamide
TL;DR: (2E)-N-(5-{4-[(difluoromethyl)sulfanyl]benzyl}-1,3-thiazol-2-yl)-3-(furan-2-yl)prop-2-enamide (CAS 496771-31-4) is a chemical compound with molecular formula C18H14F2N2O2S2 and molecular weight 392.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-N-[5-[[4-(difluoromethylsulfanyl)phenyl]methyl]-1,3-thiazol-2-yl]-3-(furan-2-yl)prop-2-enamide
Also Known As: (2E)-N-(5-{4-[(difluoromethyl)sulfanyl]benzyl}-1,3-thiazol-2-yl)-3-(furan-2-yl)prop-2-enamide, (E)-N-(5-(4-((difluoromethyl)thio)benzyl)thiazol-2-yl)-3-(furan-2-yl)acrylamide, (2E)-N-(5-{[4-(difluoromethylthio)phenyl]methyl}(1,3-thiazol-2-yl))-3-(2-furyl )prop-2-enamide, (E)-N-[5-[[4-(difluoromethylsulfanyl)phenyl]methyl]-1,3-thiazol-2-yl]-3-(furan-2-yl)prop-2-enamide
| Molecular Formula | C18H14F2N2O2S2 |
|---|---|
| Molecular Weight | 392.05 g/mol |
| LogP | 5.2935 |
| Topological Polar Surface Area | 55.13 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 7 |
| Exact Mass | 392.04648 |
| Heavy Atoms | 26 |
| Complexity | 875.00037 |
Chemical Identifiers
| CAS Number | 496771-31-4 |
|---|---|
| SMILES | C1=COC(=C1)/C=C/C(=O)NC2=NC=C(S2)CC3=CC=C(C=C3)SC(F)F |
Product Overview
(2E)-N-(5-{4-[(difluoromethyl)sulfanyl]benzyl}-1,3-thiazol-2-yl)-3-(furan-2-yl)prop-2-enamide (CAS 496771-31-4), with molecular formula C18H14F2N2O2S2 and molecular weight 392.05 g/mol. IUPAC: (E)-N-[5-[[4-(difluoromethylsulfanyl)phenyl]methyl]-1,3-thiazol-2-yl]-3-(furan-2-yl)prop-2-enamide.
Chemical Property Profile of (2E)-N-(5-{4-[(difluoromethyl)sulfanyl]benzyl}-1,3-thiazol-2-yl)-3-(furan-2-yl)prop-2-enamide
Property Insights of (2E)-N-(5-{4-[(difluoromethyl)sulfanyl]benzyl}-1,3-thiazol-2-yl)-3-(furan-2-yl)prop-2-enamide
The XLogP value of 5.2935 indicates that (2E)-N-(5-{4-[(difluoromethyl)sulfanyl]benzyl}-1,3-thiazol-2-yl)-3-(furan-2-yl)prop-2-enamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 55.13 Ų, (2E)-N-(5-{4-[(difluoromethyl)sulfanyl]benzyl}-1,3-thiazol-2-yl)-3-(furan-2-yl)prop-2-enamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (2E)-N-(5-{4-[(difluoromethyl)sulfanyl]benzyl}-1,3-thiazol-2-yl)-3-(furan-2-yl)prop-2-enamide has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (2E)-N-(5-{4-[(difluoromethyl)sulfanyl]benzyl}-1,3-thiazol-2-yl)-3-(furan-2-yl)prop-2-enamide?
The CAS number of (2E)-N-(5-{4-[(difluoromethyl)sulfanyl]benzyl}-1,3-thiazol-2-yl)-3-(furan-2-yl)prop-2-enamide is 496771-31-4.
What is the molecular formula of (2E)-N-(5-{4-[(difluoromethyl)sulfanyl]benzyl}-1,3-thiazol-2-yl)-3-(furan-2-yl)prop-2-enamide?
The molecular formula of (2E)-N-(5-{4-[(difluoromethyl)sulfanyl]benzyl}-1,3-thiazol-2-yl)-3-(furan-2-yl)prop-2-enamide is C18H14F2N2O2S2.
What is the molecular weight of (2E)-N-(5-{4-[(difluoromethyl)sulfanyl]benzyl}-1,3-thiazol-2-yl)-3-(furan-2-yl)prop-2-enamide?
The molecular weight of (2E)-N-(5-{4-[(difluoromethyl)sulfanyl]benzyl}-1,3-thiazol-2-yl)-3-(furan-2-yl)prop-2-enamide is 392.05 g/mol.
Where can I buy (2E)-N-(5-{4-[(difluoromethyl)sulfanyl]benzyl}-1,3-thiazol-2-yl)-3-(furan-2-yl)prop-2-enamide?
You can request a quote for (2E)-N-(5-{4-[(difluoromethyl)sulfanyl]benzyl}-1,3-thiazol-2-yl)-3-(furan-2-yl)prop-2-enamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (2E)-N-(5-{4-[(difluoromethyl)sulfanyl]benzyl}-1,3-thiazol-2-yl)-3-(furan-2-yl)prop-2-enamide?
Yes, KEHONG BIO provides custom synthesis services for (2E)-N-(5-{4-[(difluoromethyl)sulfanyl]benzyl}-1,3-thiazol-2-yl)-3-(furan-2-yl)prop-2-enamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.