(E)-N-(4-(indolin-1-ylsulfonyl)phenyl)-3-(4-methoxyphenyl)acrylamide
TL;DR: (E)-N-(4-(indolin-1-ylsulfonyl)phenyl)-3-(4-methoxyphenyl)acrylamide (CAS 496032-88-3) is a chemical compound with molecular formula C24H22N2O4S and molecular weight 434.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-N-[4-(2,3-dihydroindol-1-ylsulfonyl)phenyl]-3-(4-methoxyphenyl)prop-2-enamide
Also Known As: AB00674409-01, F1443-3023, (E)-N-(4-(indolin-1-ylsulfonyl)phenyl)-3-(4-methoxyphenyl)acrylamide, N-[4-(2,3-dihydro-1H-indol-1-ylsulfonyl)phenyl]-3-(4-methoxyphenyl)acrylamide, (2E)-N-[4-(2,3-dihydro-1H-indol-1-ylsulfonyl)phenyl]-3-(4-methoxyphenyl)prop-2-enamide
| Molecular Formula | C24H22N2O4S |
|---|---|
| Molecular Weight | 434.13 g/mol |
| LogP | 4.0985 |
| Topological Polar Surface Area | 75.71 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 6 |
| Exact Mass | 434.13004 |
| Heavy Atoms | 31 |
| Complexity | 1217.194 |
Chemical Identifiers
| CAS Number | 496032-88-3 |
|---|---|
| SMILES | COC1=CC=C(C=C1)/C=C/C(=O)NC2=CC=C(C=C2)S(=O)(=O)N3CCC4=CC=CC=C43 |
Product Overview
(E)-N-(4-(indolin-1-ylsulfonyl)phenyl)-3-(4-methoxyphenyl)acrylamide (CAS 496032-88-3), with molecular formula C24H22N2O4S and molecular weight 434.13 g/mol. IUPAC: (E)-N-[4-(2,3-dihydroindol-1-ylsulfonyl)phenyl]-3-(4-methoxyphenyl)prop-2-enamide.
Chemical Property Profile of (E)-N-(4-(indolin-1-ylsulfonyl)phenyl)-3-(4-methoxyphenyl)acrylamide
Property Insights of (E)-N-(4-(indolin-1-ylsulfonyl)phenyl)-3-(4-methoxyphenyl)acrylamide
The XLogP value of 4.0985 indicates that (E)-N-(4-(indolin-1-ylsulfonyl)phenyl)-3-(4-methoxyphenyl)acrylamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 75.71 Ų falls within the moderate polarity range, balancing permeability and solubility for (E)-N-(4-(indolin-1-ylsulfonyl)phenyl)-3-(4-methoxyphenyl)acrylamide. Following Lipinski's Rule of Five, (E)-N-(4-(indolin-1-ylsulfonyl)phenyl)-3-(4-methoxyphenyl)acrylamide has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-N-(4-(indolin-1-ylsulfonyl)phenyl)-3-(4-methoxyphenyl)acrylamide?
The CAS number of (E)-N-(4-(indolin-1-ylsulfonyl)phenyl)-3-(4-methoxyphenyl)acrylamide is 496032-88-3.
What is the molecular formula of (E)-N-(4-(indolin-1-ylsulfonyl)phenyl)-3-(4-methoxyphenyl)acrylamide?
The molecular formula of (E)-N-(4-(indolin-1-ylsulfonyl)phenyl)-3-(4-methoxyphenyl)acrylamide is C24H22N2O4S.
What is the molecular weight of (E)-N-(4-(indolin-1-ylsulfonyl)phenyl)-3-(4-methoxyphenyl)acrylamide?
The molecular weight of (E)-N-(4-(indolin-1-ylsulfonyl)phenyl)-3-(4-methoxyphenyl)acrylamide is 434.13 g/mol.
Where can I buy (E)-N-(4-(indolin-1-ylsulfonyl)phenyl)-3-(4-methoxyphenyl)acrylamide?
You can request a quote for (E)-N-(4-(indolin-1-ylsulfonyl)phenyl)-3-(4-methoxyphenyl)acrylamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-N-(4-(indolin-1-ylsulfonyl)phenyl)-3-(4-methoxyphenyl)acrylamide?
Yes, KEHONG BIO provides custom synthesis services for (E)-N-(4-(indolin-1-ylsulfonyl)phenyl)-3-(4-methoxyphenyl)acrylamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.