AF-399/40923352 structure

AF-399/40923352

TL;DR: AF-399/40923352 (CAS 496022-86-7) is a chemical compound with molecular formula C22H20FN3OS2 and molecular weight 425.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)sulfanyl-1-[1-(2-fluorophenyl)-2,5-dimethylpyrrol-3-yl]ethanone

Also Known As: AF-399/40923352, 2-[(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)sulfanyl]-1-[1-(2-fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]ethanone, 2-(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)sulfanyl-1-[1-(2-fluorophenyl)-2,5-dimethylpyrrol-3-yl]ethanone, 2-(5,6-dimethylthiopheno[3,2-e]pyrimidin-4-ylthio)-1-[1-(2-fluorophenyl)-2,5-d imethylpyrrol-3-yl]ethan-1-one

CAS: 496022-86-7
Molecular Formula C22H20FN3OS2
Molecular Weight 425.10 g/mol
LogP 5.82978
Topological Polar Surface Area 47.78 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 5
Rotatable Bonds 5
Exact Mass 425.10318
Heavy Atoms 29
Complexity 1242.5652

Chemical Identifiers

CAS Number 496022-86-7
SMILES CC1=CC(=C(N1C2=CC=CC=C2F)C)C(=O)CSC3=NC=NC4=C3C(=C(S4)C)C

Product Overview

AF-399/40923352 (CAS 496022-86-7), with molecular formula C22H20FN3OS2 and molecular weight 425.10 g/mol. IUPAC: 2-(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)sulfanyl-1-[1-(2-fluorophenyl)-2,5-dimethylpyrrol-3-yl]ethanone.

🧪
Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of AF-399/40923352

XLogP
5.82978
TPSA (Topological Polar Surface Area)
47.78
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
5
Rotatable Bonds
5
Heavy Atoms
29
Complexity
1242.5652
Exact Mass
425.10318
Monoisotopic Mass
425.10318
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of AF-399/40923352

The XLogP value of 5.82978 indicates that AF-399/40923352 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 47.78 Ų, AF-399/40923352 exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, AF-399/40923352 has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of AF-399/40923352?

The CAS number of AF-399/40923352 is 496022-86-7.

What is the molecular formula of AF-399/40923352?

The molecular formula of AF-399/40923352 is C22H20FN3OS2.

What is the molecular weight of AF-399/40923352?

The molecular weight of AF-399/40923352 is 425.10 g/mol.

Where can I buy AF-399/40923352?

You can request a quote for AF-399/40923352 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for AF-399/40923352?

Yes, KEHONG BIO provides custom synthesis services for AF-399/40923352 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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