AM-807/12427364
TL;DR: AM-807/12427364 (CAS 496018-59-8) is a chemical compound with molecular formula C21H14ClF3N4O2 and molecular weight 446.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6-amino-4-[2-[(2-chlorophenyl)methoxy]phenyl]-3-(trifluoromethyl)-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile
Also Known As: AM-807/12427364, 6-amino-4-[2-[(2-chlorophenyl)methoxy]phenyl]-3-(trifluoromethyl)-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile, 6-amino-4-{2-[(2-chlorobenzyl)oxy]phenyl}-3-(trifluoromethyl)-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile
| Molecular Formula | C21H14ClF3N4O2 |
|---|---|
| Molecular Weight | 446.08 g/mol |
| LogP | 4.87908 |
| Topological Polar Surface Area | 96.95 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 446.07574 |
| Heavy Atoms | 31 |
| Complexity | 1213.8193 |
Chemical Identifiers
| CAS Number | 496018-59-8 |
|---|---|
| SMILES | C1=CC=C(C(=C1)COC2=CC=CC=C2C3C(=C(OC4=NNC(=C34)C(F)(F)F)N)C#N)Cl |
Product Overview
AM-807/12427364 (CAS 496018-59-8), with molecular formula C21H14ClF3N4O2 and molecular weight 446.08 g/mol. IUPAC: 6-amino-4-[2-[(2-chlorophenyl)methoxy]phenyl]-3-(trifluoromethyl)-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile.
Chemical Property Profile of AM-807/12427364
Property Insights of AM-807/12427364
The XLogP value of 4.87908 indicates that AM-807/12427364 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 96.95 Ų falls within the moderate polarity range, balancing permeability and solubility for AM-807/12427364. Following Lipinski's Rule of Five, AM-807/12427364 has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of AM-807/12427364?
The CAS number of AM-807/12427364 is 496018-59-8.
What is the molecular formula of AM-807/12427364?
The molecular formula of AM-807/12427364 is C21H14ClF3N4O2.
What is the molecular weight of AM-807/12427364?
The molecular weight of AM-807/12427364 is 446.08 g/mol.
Where can I buy AM-807/12427364?
You can request a quote for AM-807/12427364 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for AM-807/12427364?
Yes, KEHONG BIO provides custom synthesis services for AM-807/12427364 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.