Midamaline
TL;DR: Midamaline (CAS 496-38-8) is a chemical compound with molecular formula C18H21ClN4 and molecular weight 328.15 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N'-[(6-chloro-1H-benzimidazol-2-yl)methyl]-N,N-dimethyl-N'-phenylethane-1,2-diamine
Also Known As: Midamaline, Midamalina, Midamalin, Midamalinum, Midamaline [INN]
| Molecular Formula | C18H21ClN4 |
|---|---|
| Molecular Weight | 328.15 g/mol |
| LogP | 3.8 |
| Topological Polar Surface Area | 35.2 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 6 |
| Exact Mass | 328.14548 |
| Heavy Atoms | 23 |
| Complexity | 359.0 |
Chemical Identifiers
| CAS Number | 496-38-8 |
|---|---|
| SMILES | CN(C)CCN(CC1=NC2=C(N1)C=C(C=C2)Cl)C3=CC=CC=C3 |
| InChIKey | VFSSTMGMWLZGCO-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 1 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Midamaline (CAS 496-38-8), with molecular formula C18H21ClN4 and molecular weight 328.15 g/mol. IUPAC: N'-[(6-chloro-1H-benzimidazol-2-yl)methyl]-N,N-dimethyl-N'-phenylethane-1,2-diamine.
Chemical Property Profile of Midamaline
Property Insights of Midamaline
The XLogP value of 3.8 indicates that Midamaline is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 35.2 Ų, Midamaline exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Midamaline has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Midamaline?
The CAS number of Midamaline is 496-38-8.
What is the molecular formula of Midamaline?
The molecular formula of Midamaline is C18H21ClN4.
What is the molecular weight of Midamaline?
The molecular weight of Midamaline is 328.15 g/mol.
Where can I buy Midamaline?
You can request a quote for Midamaline directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Midamaline?
Yes, KEHONG BIO provides custom synthesis services for Midamaline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.