![5-chloro-N-[2-chloro-5-(trifluoromethyl)phenyl]thiophene-2-carboxamide structure](/static/products/4953/495386-07-7.webp)
5-chloro-N-[2-chloro-5-(trifluoromethyl)phenyl]thiophene-2-carboxamide
TL;DR: 5-chloro-N-[2-chloro-5-(trifluoromethyl)phenyl]thiophene-2-carboxamide (CAS 495386-07-7) is a chemical compound with molecular formula C12H6Cl2F3NOS and molecular weight 338.95 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-chloro-N-[2-chloro-5-(trifluoromethyl)phenyl]thiophene-2-carboxamide
Also Known As: 5-chloro-N-[2-chloro-5-(trifluoromethyl)phenyl]thiophene-2-carboxamide, (5-chloro(2-thienyl))-N-[2-chloro-5-(trifluoromethyl)phenyl]carboxamide, 5-chloro-N-[2-chloro-5-(trifluoromethyl)phenyl]-2-thiophenecarboxamide
| Molecular Formula | C12H6Cl2F3NOS |
|---|---|
| Molecular Weight | 338.95 g/mol |
| LogP | 5.326 |
| Topological Polar Surface Area | 29.1 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 338.94992 |
| Heavy Atoms | 20 |
| Complexity | 654.3923 |
Chemical Identifiers
| CAS Number | 495386-07-7 |
|---|---|
| SMILES | C1=CC(=C(C=C1C(F)(F)F)NC(=O)C2=CC=C(S2)Cl)Cl |
Product Overview
5-chloro-N-[2-chloro-5-(trifluoromethyl)phenyl]thiophene-2-carboxamide (CAS 495386-07-7), with molecular formula C12H6Cl2F3NOS and molecular weight 338.95 g/mol. IUPAC: 5-chloro-N-[2-chloro-5-(trifluoromethyl)phenyl]thiophene-2-carboxamide.
Chemical Property Profile of 5-chloro-N-[2-chloro-5-(trifluoromethyl)phenyl]thiophene-2-carboxamide
Property Insights of 5-chloro-N-[2-chloro-5-(trifluoromethyl)phenyl]thiophene-2-carboxamide
The XLogP value of 5.326 indicates that 5-chloro-N-[2-chloro-5-(trifluoromethyl)phenyl]thiophene-2-carboxamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 29.1 Ų, 5-chloro-N-[2-chloro-5-(trifluoromethyl)phenyl]thiophene-2-carboxamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 5-chloro-N-[2-chloro-5-(trifluoromethyl)phenyl]thiophene-2-carboxamide has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-chloro-N-[2-chloro-5-(trifluoromethyl)phenyl]thiophene-2-carboxamide?
The CAS number of 5-chloro-N-[2-chloro-5-(trifluoromethyl)phenyl]thiophene-2-carboxamide is 495386-07-7.
What is the molecular formula of 5-chloro-N-[2-chloro-5-(trifluoromethyl)phenyl]thiophene-2-carboxamide?
The molecular formula of 5-chloro-N-[2-chloro-5-(trifluoromethyl)phenyl]thiophene-2-carboxamide is C12H6Cl2F3NOS.
What is the molecular weight of 5-chloro-N-[2-chloro-5-(trifluoromethyl)phenyl]thiophene-2-carboxamide?
The molecular weight of 5-chloro-N-[2-chloro-5-(trifluoromethyl)phenyl]thiophene-2-carboxamide is 338.95 g/mol.
Where can I buy 5-chloro-N-[2-chloro-5-(trifluoromethyl)phenyl]thiophene-2-carboxamide?
You can request a quote for 5-chloro-N-[2-chloro-5-(trifluoromethyl)phenyl]thiophene-2-carboxamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-chloro-N-[2-chloro-5-(trifluoromethyl)phenyl]thiophene-2-carboxamide?
Yes, KEHONG BIO provides custom synthesis services for 5-chloro-N-[2-chloro-5-(trifluoromethyl)phenyl]thiophene-2-carboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.