AM-807/12740137
TL;DR: AM-807/12740137 (CAS 494792-12-0) is a chemical compound with molecular formula C18H13Cl2N5 and molecular weight 369.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(8R,8aR)-6-amino-8-(2,3-dichlorophenyl)-2,3,8,8a-tetrahydro-1H-isoquinoline-5,7,7-tricarbonitrile
Also Known As: AM-807/12740137, 6-amino-8-(2,3-dichlorophenyl)-2,3,8,8a-tetrahydro-5,7,7(1H)-isoquinolinetricarbonitrile, (8R,8aR)-6-amino-8-(2,3-dichlorophenyl)-2,3,8,8a-tetrahydro-1H-isoquinoline-5,7,7-tricarbonitrile, (8R,8aR)-6-amino-8-(2,3-dichlorophenyl)-2,3,8,8a-tetrahydroisoquinoline-5,7,7(1H)-tricarbonitrile
| Molecular Formula | C18H13Cl2N5 |
|---|---|
| Molecular Weight | 369.05 g/mol |
| LogP | 3.00634 |
| Topological Polar Surface Area | 109.42 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 1 |
| Exact Mass | 369.0548 |
| Heavy Atoms | 25 |
| Complexity | 912.25555 |
Chemical Identifiers
| CAS Number | 494792-12-0 |
|---|---|
| SMILES | C1C=C2[C@H](CN1)[C@H](C(C(=C2C#N)N)(C#N)C#N)C3=C(C(=CC=C3)Cl)Cl |
Product Overview
AM-807/12740137 (CAS 494792-12-0), with molecular formula C18H13Cl2N5 and molecular weight 369.05 g/mol. IUPAC: (8R,8aR)-6-amino-8-(2,3-dichlorophenyl)-2,3,8,8a-tetrahydro-1H-isoquinoline-5,7,7-tricarbonitrile.
Chemical Property Profile of AM-807/12740137
Property Insights of AM-807/12740137
The XLogP value of 3.00634 indicates that AM-807/12740137 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 109.42 Ų falls within the moderate polarity range, balancing permeability and solubility for AM-807/12740137. Following Lipinski's Rule of Five, AM-807/12740137 has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of AM-807/12740137?
The CAS number of AM-807/12740137 is 494792-12-0.
What is the molecular formula of AM-807/12740137?
The molecular formula of AM-807/12740137 is C18H13Cl2N5.
What is the molecular weight of AM-807/12740137?
The molecular weight of AM-807/12740137 is 369.05 g/mol.
Where can I buy AM-807/12740137?
You can request a quote for AM-807/12740137 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for AM-807/12740137?
Yes, KEHONG BIO provides custom synthesis services for AM-807/12740137 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.