AM-807/12740122 structure

AM-807/12740122

TL;DR: AM-807/12740122 (CAS 494792-08-4) is a chemical compound with molecular formula C24H27N5O2 and molecular weight 417.22 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

(8S,8aR)-6-amino-8-(3-ethoxy-4-propan-2-yloxyphenyl)-2-methyl-1,3,8,8a-tetrahydroisoquinoline-5,7,7-tricarbonitrile

Also Known As: AM-807/12740122, (8S,8aR)-6-amino-8-(3-ethoxy-4-isopropoxyphenyl)-2-methyl-2,3,8,8a-tetrahydroisoquinoline-5,7,7(1H)-tricarbonitrile, (8S,8aR)-6-amino-8-(3-ethoxy-4-propan-2-yloxyphenyl)-2-methyl-1,3,8,8a-tetrahydroisoquinoline-5,7,7-tricarbonitrile, 6-amino-8-(3-ethoxy-4-isopropoxyphenyl)-2-methyl-2,3,8,8a-tetrahydro-5,7,7(1H)-isoquinolinetricarbonitrile

CAS: 494792-08-4
Molecular Formula C24H27N5O2
Molecular Weight 417.22 g/mol
LogP 3.22764
Topological Polar Surface Area 119.09 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 7
Rotatable Bonds 5
Exact Mass 417.21646
Heavy Atoms 31
Complexity 1037.1987

Chemical Identifiers

CAS Number 494792-08-4
SMILES CCOC1=C(C=CC(=C1)[C@@H]2[C@H]3CN(CC=C3C(=C(C2(C#N)C#N)N)C#N)C)OC(C)C

Product Overview

AM-807/12740122 (CAS 494792-08-4), with molecular formula C24H27N5O2 and molecular weight 417.22 g/mol. IUPAC: (8S,8aR)-6-amino-8-(3-ethoxy-4-propan-2-yloxyphenyl)-2-methyl-1,3,8,8a-tetrahydroisoquinoline-5,7,7-tricarbonitrile.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of AM-807/12740122

XLogP
3.22764
TPSA (Topological Polar Surface Area)
119.09
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
7
Rotatable Bonds
5
Heavy Atoms
31
Complexity
1037.1987
Exact Mass
417.21646
Monoisotopic Mass
417.21646
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of AM-807/12740122

The XLogP value of 3.22764 indicates that AM-807/12740122 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 119.09 Ų falls within the moderate polarity range, balancing permeability and solubility for AM-807/12740122. Following Lipinski's Rule of Five, AM-807/12740122 has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of AM-807/12740122?

The CAS number of AM-807/12740122 is 494792-08-4.

What is the molecular formula of AM-807/12740122?

The molecular formula of AM-807/12740122 is C24H27N5O2.

What is the molecular weight of AM-807/12740122?

The molecular weight of AM-807/12740122 is 417.22 g/mol.

Where can I buy AM-807/12740122?

You can request a quote for AM-807/12740122 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for AM-807/12740122?

Yes, KEHONG BIO provides custom synthesis services for AM-807/12740122 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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