![N-[(E)-(2-methylpyrazol-3-yl)methylideneamino]-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide structure](/static/products/494/494220-12-1.png)
N-[(E)-(2-methylpyrazol-3-yl)methylideneamino]-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide
概要：N-[(E)-(2-methylpyrazol-3-yl)methylideneamino]-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide（CAS 494220-12-1）是一种化学化合物，分子式为C17H12F3N7OS，分子量为419.08 g/mol。河南科弘生物科技有限公司提供CRO/CDMO定制合成服务，支持克级到吨级规格。
N-[(E)-(2-methylpyrazol-3-yl)methylideneamino]-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide
又称：N-[(E)-(2-methylpyrazol-3-yl)methylideneamino]-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide, N'-[(1-methyl-1H-pyrazol-5-yl)methylene]-5-(2-thienyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbohydrazide, N'-[(E)-(1-methyl-1H-pyrazol-5-yl)methylidene]-5-(thiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbohydrazide
| 分子式 | C17H12F3N7OS |
|---|---|
| 分子量 | 419.08 g/mol |
| LogP | 2.974 |
| 拓扑极性表面积 | 89.47 Ų |
| 氢键供体数 | 1 |
| 氢键受体数 | 6 |
| 可旋转键数 | 4 |
| 精确质量 | 419.0776 |
| 重原子数 | 29 |
| 复杂度 | 1207.7981 |
化学标识符
| CAS 编号 | 494220-12-1 |
|---|---|
| SMILES | CN1C(=CC=N1)/C=N/NC(=O)C2=NN3C(=CC(=NC3=C2)C4=CC=CS4)C(F)(F)F |
产品概述
N-[(E)-(2-methylpyrazol-3-yl)methylideneamino]-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide（CAS 494220-12-1），分子式为C17H12F3N7OS，分子量为419.08 g/mol。IUPAC名：N-[(E)-(2-methylpyrazol-3-yl)methylideneamino]-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide。
N-[(E)-(2-methylpyrazol-3-yl)methylideneamino]-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide化学性质概览
属性洞察：N-[(E)-(2-methylpyrazol-3-yl)methylideneamino]-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide
N-[(E)-(2-methylpyrazol-3-yl)methylideneamino]-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide的XLogP值为2.974，表明具有中等亲脂性，在水溶性和膜透过性之间取得平衡。 TPSA为89.47 Ų，处于中等极性范围，在透过性和溶解性之间取得平衡。 根据Lipinski五规则，N-[(E)-(2-methylpyrazol-3-yl)methylideneamino]-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide有1个氢键供体和6个氢键受体，均在类药范围内，提示具有较好的口服生物利用度潜力。
常见问题
常见问题
N-[(E)-(2-methylpyrazol-3-yl)methylideneamino]-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide的CAS号是多少？
N-[(E)-(2-methylpyrazol-3-yl)methylideneamino]-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide的CAS号为494220-12-1。
N-[(E)-(2-methylpyrazol-3-yl)methylideneamino]-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide的分子式是什么？
N-[(E)-(2-methylpyrazol-3-yl)methylideneamino]-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide的分子式为C17H12F3N7OS。
N-[(E)-(2-methylpyrazol-3-yl)methylideneamino]-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide的分子量是多少？
N-[(E)-(2-methylpyrazol-3-yl)methylideneamino]-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide的分子量为419.08 g/mol。
在哪里可以购买N-[(E)-(2-methylpyrazol-3-yl)methylideneamino]-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide？
您可以直接向科弘生物询价N-[(E)-(2-methylpyrazol-3-yl)methylideneamino]-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide。联系我们或发送邮件至info@kehongbio.com获取报价和库存信息。
科弘生物是否提供N-[(E)-(2-methylpyrazol-3-yl)methylideneamino]-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide的定制合成服务？
是的，科弘生物提供N-[(E)-(2-methylpyrazol-3-yl)methylideneamino]-5-thiophen-2-yl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxamide及相关化合物的定制合成服务。请联系我们并告知您的具体需求，包括数量、纯度和交期。