Nornicotine
TL;DR: Nornicotine (CAS 494-97-3) is a chemical compound with molecular formula C9H12N2 and molecular weight 148.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-[(2S)-pyrrolidin-2-yl]pyridine
Also Known As: nornicotine, l-Nor-nicotine, (S)-Nornicotine, Nornicotin, (S)-3-(Pyrrolidin-2-yl)pyridine
| Molecular Formula | C9H12N2 |
|---|---|
| Molecular Weight | 148.10 g/mol |
| LogP | 0.2 |
| Topological Polar Surface Area | 24.9 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 1 |
| Exact Mass | 148.10005 |
| Heavy Atoms | 11 |
| Complexity | 125.0 |
| Boiling Point | 260 °C |
| Density | 1.0737 at 20 °C |
| Solubility | Miscible in water; Very soluble in alcohol, chloroform, ether, petr ether, kerosene, oils |
| Vapor Pressure | 0.0097 [mmHg] |
| Refractive Index | 1.5378 at 20 °C |
Chemical Identifiers
| CAS Number | 494-97-3 |
|---|---|
| SMILES | C1C[C@H](NC1)C2=CN=CC=C2 |
| InChIKey | MYKUKUCHPMASKF-VIFPVBQESA-N |
Patent-Derived Application Labels
Derived from 16 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Nornicotine (CAS 494-97-3), with molecular formula C9H12N2 and molecular weight 148.10 g/mol. IUPAC: 3-[(2S)-pyrrolidin-2-yl]pyridine.
Chemical Property Profile of Nornicotine
Property Insights of Nornicotine
The XLogP value of 0.2 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Nornicotine. With a topological polar surface area (TPSA) of 24.9 Ų, Nornicotine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Nornicotine has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Nornicotine?
The CAS number of Nornicotine is 494-97-3.
What is the molecular formula of Nornicotine?
The molecular formula of Nornicotine is C9H12N2.
What is the molecular weight of Nornicotine?
The molecular weight of Nornicotine is 148.10 g/mol.
Where can I buy Nornicotine?
You can request a quote for Nornicotine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Nornicotine?
Yes, KEHONG BIO provides custom synthesis services for Nornicotine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.