![7-(Difluoromethyl)-5-(4-methoxyphenyl)-N-[4-(1-piperidinylcarbonyl)phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide structure](/static/products/4924/492433-51-9.webp)
7-(Difluoromethyl)-5-(4-methoxyphenyl)-N-[4-(1-piperidinylcarbonyl)phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
TL;DR: 7-(Difluoromethyl)-5-(4-methoxyphenyl)-N-[4-(1-piperidinylcarbonyl)phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide (CAS 492433-51-9) is a chemical compound with molecular formula C27H25F2N5O3 and molecular weight 505.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
7-(difluoromethyl)-5-(4-methoxyphenyl)-N-[4-(piperidine-1-carbonyl)phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
Also Known As: 7-(Difluoromethyl)-5-(4-methoxyphenyl)-N-[4-(1-piperidinylcarbonyl)phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide, 7-(difluoromethyl)-5-(4-methoxyphenyl)-N-[4-(piperidin-1-ylcarbonyl)phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide, 7-(difluoromethyl)-5-(4-methoxyphenyl)-N-[4-(piperidine-1-carbonyl)phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide, 7-(Difluoromethyl)-5-(4-methoxyphenyl)-N-(4-(1-piperidinylcarbonyl)phenyl)pyrazolo(1,5-a)pyrimidine-3-carboxamide, 7-(DIFLUOROMETHYL)-5-(4-METHOXYPHENYL)-N-[4-(PIPERIDINOCARBONYL)PHENYL]PYRAZOLO[1,5-A]PYRIMIDINE-3-CARBOXAMIDE
| Molecular Formula | C27H25F2N5O3 |
|---|---|
| Molecular Weight | 505.19 g/mol |
| LogP | 5.2209 |
| Topological Polar Surface Area | 88.83 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Exact Mass | 505.19254 |
| Heavy Atoms | 37 |
| Complexity | 1429.2113 |
Chemical Identifiers
| CAS Number | 492433-51-9 |
|---|---|
| SMILES | COC1=CC=C(C=C1)C2=NC3=C(C=NN3C(=C2)C(F)F)C(=O)NC4=CC=C(C=C4)C(=O)N5CCCCC5 |
Product Overview
7-(Difluoromethyl)-5-(4-methoxyphenyl)-N-[4-(1-piperidinylcarbonyl)phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide (CAS 492433-51-9), with molecular formula C27H25F2N5O3 and molecular weight 505.19 g/mol. IUPAC: 7-(difluoromethyl)-5-(4-methoxyphenyl)-N-[4-(piperidine-1-carbonyl)phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide.
Chemical Property Profile of 7-(Difluoromethyl)-5-(4-methoxyphenyl)-N-[4-(1-piperidinylcarbonyl)phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
Property Insights of 7-(Difluoromethyl)-5-(4-methoxyphenyl)-N-[4-(1-piperidinylcarbonyl)phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide
The XLogP value of 5.2209 indicates that 7-(Difluoromethyl)-5-(4-methoxyphenyl)-N-[4-(1-piperidinylcarbonyl)phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 88.83 Ų falls within the moderate polarity range, balancing permeability and solubility for 7-(Difluoromethyl)-5-(4-methoxyphenyl)-N-[4-(1-piperidinylcarbonyl)phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide. Following Lipinski's Rule of Five, 7-(Difluoromethyl)-5-(4-methoxyphenyl)-N-[4-(1-piperidinylcarbonyl)phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 7-(Difluoromethyl)-5-(4-methoxyphenyl)-N-[4-(1-piperidinylcarbonyl)phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide?
The CAS number of 7-(Difluoromethyl)-5-(4-methoxyphenyl)-N-[4-(1-piperidinylcarbonyl)phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide is 492433-51-9.
What is the molecular formula of 7-(Difluoromethyl)-5-(4-methoxyphenyl)-N-[4-(1-piperidinylcarbonyl)phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide?
The molecular formula of 7-(Difluoromethyl)-5-(4-methoxyphenyl)-N-[4-(1-piperidinylcarbonyl)phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide is C27H25F2N5O3.
What is the molecular weight of 7-(Difluoromethyl)-5-(4-methoxyphenyl)-N-[4-(1-piperidinylcarbonyl)phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide?
The molecular weight of 7-(Difluoromethyl)-5-(4-methoxyphenyl)-N-[4-(1-piperidinylcarbonyl)phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide is 505.19 g/mol.
Where can I buy 7-(Difluoromethyl)-5-(4-methoxyphenyl)-N-[4-(1-piperidinylcarbonyl)phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide?
You can request a quote for 7-(Difluoromethyl)-5-(4-methoxyphenyl)-N-[4-(1-piperidinylcarbonyl)phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 7-(Difluoromethyl)-5-(4-methoxyphenyl)-N-[4-(1-piperidinylcarbonyl)phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide?
Yes, KEHONG BIO provides custom synthesis services for 7-(Difluoromethyl)-5-(4-methoxyphenyl)-N-[4-(1-piperidinylcarbonyl)phenyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.