Nicopholine
TL;DR: Nicopholine (CAS 492-85-3) is a chemical compound with molecular formula C10H12N2O2 and molecular weight 192.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
morpholin-4-yl(pyridin-3-yl)methanone
Also Known As: Nicopholine, Nicopholinum, Nicofolina, 4-Nicotinoylmorpholin, Nicotinoylmorpholid
| Molecular Formula | C10H12N2O2 |
|---|---|
| Molecular Weight | 192.09 g/mol |
| LogP | -0.1 |
| Topological Polar Surface Area | 42.4 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 1 |
| Exact Mass | 192.08987 |
| Heavy Atoms | 14 |
| Complexity | 202.0 |
Chemical Identifiers
| CAS Number | 492-85-3 |
|---|---|
| SMILES | C1COCCN1C(=O)C2=CN=CC=C2 |
| InChIKey | QLPQPTXSAXQCMR-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 4 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Nicopholine (CAS 492-85-3), with molecular formula C10H12N2O2 and molecular weight 192.09 g/mol. IUPAC: morpholin-4-yl(pyridin-3-yl)methanone.
Chemical Property Profile of Nicopholine
Property Insights of Nicopholine
The XLogP value of -0.1 indicates that Nicopholine is hydrophilic (water-soluble), making it suitable for aqueous formulations and biological assay applications. With a topological polar surface area (TPSA) of 42.4 Ų, Nicopholine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Nicopholine has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Nicopholine?
The CAS number of Nicopholine is 492-85-3.
What is the molecular formula of Nicopholine?
The molecular formula of Nicopholine is C10H12N2O2.
What is the molecular weight of Nicopholine?
The molecular weight of Nicopholine is 192.09 g/mol.
Where can I buy Nicopholine?
You can request a quote for Nicopholine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Nicopholine?
Yes, KEHONG BIO provides custom synthesis services for Nicopholine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.