N-(2,4-Difluorophenyl)-2-(4-(diphenylmethyl)piperazinyl)ethanamide structure

N-(2,4-Difluorophenyl)-2-(4-(diphenylmethyl)piperazinyl)ethanamide

TL;DR: N-(2,4-Difluorophenyl)-2-(4-(diphenylmethyl)piperazinyl)ethanamide (CAS 491867-86-8) is a chemical compound with molecular formula C25H25F2N3O and molecular weight 421.20 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

2-(4-benzhydrylpiperazin-1-yl)-N-(2,4-difluorophenyl)acetamide

Also Known As: 2-(4-benzhydrylpiperazin-1-yl)-N-(2,4-difluorophenyl)acetamide, N-(2,4-DIFLUOROPHENYL)-2-(4-(DIPHENYLMETHYL)PIPERAZINYL)ETHANAMIDE, AO-990/40758371, N-(2,4-difluorophenyl)-2-[4-(diphenylmethyl)piperazin-1-yl]acetamide, 2-(4-benzhydryl-1-piperazinyl)-N-(2,4-difluorophenyl)acetamide

CAS: 491867-86-8
Molecular Formula C25H25F2N3O
Molecular Weight 421.20 g/mol
LogP 4.3105
Topological Polar Surface Area 35.58 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 3
Rotatable Bonds 6
Exact Mass 421.19656
Heavy Atoms 31
Complexity 966.2904

Chemical Identifiers

CAS Number 491867-86-8
SMILES C1CN(CCN1CC(=O)NC2=C(C=C(C=C2)F)F)C(C3=CC=CC=C3)C4=CC=CC=C4

Product Overview

N-(2,4-Difluorophenyl)-2-(4-(diphenylmethyl)piperazinyl)ethanamide (CAS 491867-86-8), with molecular formula C25H25F2N3O and molecular weight 421.20 g/mol. IUPAC: 2-(4-benzhydrylpiperazin-1-yl)-N-(2,4-difluorophenyl)acetamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of N-(2,4-Difluorophenyl)-2-(4-(diphenylmethyl)piperazinyl)ethanamide

XLogP
4.3105
TPSA (Topological Polar Surface Area)
35.58
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
3
Rotatable Bonds
6
Heavy Atoms
31
Complexity
966.2904
Exact Mass
421.19656
Monoisotopic Mass
421.19656
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of N-(2,4-Difluorophenyl)-2-(4-(diphenylmethyl)piperazinyl)ethanamide

The XLogP value of 4.3105 indicates that N-(2,4-Difluorophenyl)-2-(4-(diphenylmethyl)piperazinyl)ethanamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 35.58 Ų, N-(2,4-Difluorophenyl)-2-(4-(diphenylmethyl)piperazinyl)ethanamide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, N-(2,4-Difluorophenyl)-2-(4-(diphenylmethyl)piperazinyl)ethanamide has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of N-(2,4-Difluorophenyl)-2-(4-(diphenylmethyl)piperazinyl)ethanamide?

The CAS number of N-(2,4-Difluorophenyl)-2-(4-(diphenylmethyl)piperazinyl)ethanamide is 491867-86-8.

What is the molecular formula of N-(2,4-Difluorophenyl)-2-(4-(diphenylmethyl)piperazinyl)ethanamide?

The molecular formula of N-(2,4-Difluorophenyl)-2-(4-(diphenylmethyl)piperazinyl)ethanamide is C25H25F2N3O.

What is the molecular weight of N-(2,4-Difluorophenyl)-2-(4-(diphenylmethyl)piperazinyl)ethanamide?

The molecular weight of N-(2,4-Difluorophenyl)-2-(4-(diphenylmethyl)piperazinyl)ethanamide is 421.20 g/mol.

Where can I buy N-(2,4-Difluorophenyl)-2-(4-(diphenylmethyl)piperazinyl)ethanamide?

You can request a quote for N-(2,4-Difluorophenyl)-2-(4-(diphenylmethyl)piperazinyl)ethanamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for N-(2,4-Difluorophenyl)-2-(4-(diphenylmethyl)piperazinyl)ethanamide?

Yes, KEHONG BIO provides custom synthesis services for N-(2,4-Difluorophenyl)-2-(4-(diphenylmethyl)piperazinyl)ethanamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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