(Z)-2-(4-(4-chlorobenzyl)piperazin-1-yl)-N'-(1-(3,4-dichlorophenyl)ethylidene)acetohydrazide
TL;DR: (Z)-2-(4-(4-chlorobenzyl)piperazin-1-yl)-N'-(1-(3,4-dichlorophenyl)ethylidene)acetohydrazide (CAS 489441-57-8) is a chemical compound with molecular formula C21H23Cl3N4O and molecular weight 452.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[4-[(4-chlorophenyl)methyl]piperazin-1-yl]-N-[(Z)-1-(3,4-dichlorophenyl)ethylideneamino]acetamide
Also Known As: (Z)-2-(4-(4-chlorobenzyl)piperazin-1-yl)-N'-(1-(3,4-dichlorophenyl)ethylidene)acetohydrazide, 2-[4-(4-chlorobenzyl)piperazin-1-yl]-N'-[(1Z)-1-(3,4-dichlorophenyl)ethylidene]acetohydrazide, 2-[4-[(4-chlorophenyl)methyl]piperazin-1-yl]-N-[(Z)-1-(3,4-dichlorophenyl)ethylideneamino]acetamide, N-[(1Z)-2-(3,4-dichlorophenyl)-1-azaprop-1-enyl]-2-{4-[(4-chlorophenyl)methyl] piperazinyl}acetamide
| Molecular Formula | C21H23Cl3N4O |
|---|---|
| Molecular Weight | 452.09 g/mol |
| LogP | 4.3048 |
| Topological Polar Surface Area | 47.94 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 6 |
| Exact Mass | 452.09375 |
| Heavy Atoms | 29 |
| Complexity | 877.995 |
Chemical Identifiers
| CAS Number | 489441-57-8 |
|---|---|
| SMILES | C/C(=N/NC(=O)CN1CCN(CC1)CC2=CC=C(C=C2)Cl)/C3=CC(=C(C=C3)Cl)Cl |
Product Overview
(Z)-2-(4-(4-chlorobenzyl)piperazin-1-yl)-N'-(1-(3,4-dichlorophenyl)ethylidene)acetohydrazide (CAS 489441-57-8), with molecular formula C21H23Cl3N4O and molecular weight 452.09 g/mol. IUPAC: 2-[4-[(4-chlorophenyl)methyl]piperazin-1-yl]-N-[(Z)-1-(3,4-dichlorophenyl)ethylideneamino]acetamide.
Chemical Property Profile of (Z)-2-(4-(4-chlorobenzyl)piperazin-1-yl)-N'-(1-(3,4-dichlorophenyl)ethylidene)acetohydrazide
Property Insights of (Z)-2-(4-(4-chlorobenzyl)piperazin-1-yl)-N'-(1-(3,4-dichlorophenyl)ethylidene)acetohydrazide
The XLogP value of 4.3048 indicates that (Z)-2-(4-(4-chlorobenzyl)piperazin-1-yl)-N'-(1-(3,4-dichlorophenyl)ethylidene)acetohydrazide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 47.94 Ų, (Z)-2-(4-(4-chlorobenzyl)piperazin-1-yl)-N'-(1-(3,4-dichlorophenyl)ethylidene)acetohydrazide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (Z)-2-(4-(4-chlorobenzyl)piperazin-1-yl)-N'-(1-(3,4-dichlorophenyl)ethylidene)acetohydrazide has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (Z)-2-(4-(4-chlorobenzyl)piperazin-1-yl)-N'-(1-(3,4-dichlorophenyl)ethylidene)acetohydrazide?
The CAS number of (Z)-2-(4-(4-chlorobenzyl)piperazin-1-yl)-N'-(1-(3,4-dichlorophenyl)ethylidene)acetohydrazide is 489441-57-8.
What is the molecular formula of (Z)-2-(4-(4-chlorobenzyl)piperazin-1-yl)-N'-(1-(3,4-dichlorophenyl)ethylidene)acetohydrazide?
The molecular formula of (Z)-2-(4-(4-chlorobenzyl)piperazin-1-yl)-N'-(1-(3,4-dichlorophenyl)ethylidene)acetohydrazide is C21H23Cl3N4O.
What is the molecular weight of (Z)-2-(4-(4-chlorobenzyl)piperazin-1-yl)-N'-(1-(3,4-dichlorophenyl)ethylidene)acetohydrazide?
The molecular weight of (Z)-2-(4-(4-chlorobenzyl)piperazin-1-yl)-N'-(1-(3,4-dichlorophenyl)ethylidene)acetohydrazide is 452.09 g/mol.
Where can I buy (Z)-2-(4-(4-chlorobenzyl)piperazin-1-yl)-N'-(1-(3,4-dichlorophenyl)ethylidene)acetohydrazide?
You can request a quote for (Z)-2-(4-(4-chlorobenzyl)piperazin-1-yl)-N'-(1-(3,4-dichlorophenyl)ethylidene)acetohydrazide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (Z)-2-(4-(4-chlorobenzyl)piperazin-1-yl)-N'-(1-(3,4-dichlorophenyl)ethylidene)acetohydrazide?
Yes, KEHONG BIO provides custom synthesis services for (Z)-2-(4-(4-chlorobenzyl)piperazin-1-yl)-N'-(1-(3,4-dichlorophenyl)ethylidene)acetohydrazide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.