(E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(3-bromobenzylidene)-5-((4-methylpiperazin-1-yl)methyl)-1H-1,2,3-triazole-4-carbohydrazide
概要：(E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(3-bromobenzylidene)-5-((4-methylpiperazin-1-yl)methyl)-1H-1,2,3-triazole-4-carbohydrazide（CAS 489424-28-4）是一种化学化合物，分子式为C18H21BrN10O2，分子量为488.10 g/mol。河南科弘生物科技有限公司提供CRO/CDMO定制合成服务，支持克级到吨级规格。
1-(4-amino-1,2,5-oxadiazol-3-yl)-N-[(E)-(3-bromophenyl)methylideneamino]-5-[(4-methylpiperazin-1-yl)methyl]triazole-4-carboxamide
又称：(E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(3-bromobenzylidene)-5-((4-methylpiperazin-1-yl)methyl)-1H-1,2,3-triazole-4-carbohydrazide, 1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-[(E)-(3-bromophenyl)methylidene]-5-[(4-methylpiperazin-1-yl)methyl]-1H-1,2,3-triazole-4-carbohydrazide
| 分子式 | C18H21BrN10O2 |
|---|---|
| 分子量 | 488.10 g/mol |
| LogP | 0.5063 |
| 拓扑极性表面积 | 143.59 Ų |
| 氢键供体数 | 2 |
| 氢键受体数 | 10 |
| 可旋转键数 | 6 |
| 精确质量 | 488.10324 |
| 重原子数 | 31 |
| 复杂度 | 1086.7084 |
化学标识符
| CAS 编号 | 489424-28-4 |
|---|---|
| SMILES | CN1CCN(CC1)CC2=C(N=NN2C3=NON=C3N)C(=O)N/N=C/C4=CC(=CC=C4)Br |
产品概述
(E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(3-bromobenzylidene)-5-((4-methylpiperazin-1-yl)methyl)-1H-1,2,3-triazole-4-carbohydrazide（CAS 489424-28-4），分子式为C18H21BrN10O2，分子量为488.10 g/mol。IUPAC名：1-(4-amino-1,2,5-oxadiazol-3-yl)-N-[(E)-(3-bromophenyl)methylideneamino]-5-[(4-methylpiperazin-1-yl)methyl]triazole-4-carboxamide。
(E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(3-bromobenzylidene)-5-((4-methylpiperazin-1-yl)methyl)-1H-1,2,3-triazole-4-carbohydrazide化学性质概览
属性洞察：(E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(3-bromobenzylidene)-5-((4-methylpiperazin-1-yl)methyl)-1H-1,2,3-triazole-4-carbohydrazide
(E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(3-bromobenzylidene)-5-((4-methylpiperazin-1-yl)methyl)-1H-1,2,3-triazole-4-carbohydrazide的XLogP值为0.5063，表明具有中等亲脂性，在水溶性和膜透过性之间取得平衡。 TPSA为143.59 Ų，极性较高，提示该化合物膜透过性可能受限但水溶性较好。 根据Lipinski五规则，(E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(3-bromobenzylidene)-5-((4-methylpiperazin-1-yl)methyl)-1H-1,2,3-triazole-4-carbohydrazide有2个氢键供体和10个氢键受体，均在类药范围内，提示具有较好的口服生物利用度潜力。
常见问题
常见问题
(E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(3-bromobenzylidene)-5-((4-methylpiperazin-1-yl)methyl)-1H-1,2,3-triazole-4-carbohydrazide的CAS号是多少？
(E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(3-bromobenzylidene)-5-((4-methylpiperazin-1-yl)methyl)-1H-1,2,3-triazole-4-carbohydrazide的CAS号为489424-28-4。
(E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(3-bromobenzylidene)-5-((4-methylpiperazin-1-yl)methyl)-1H-1,2,3-triazole-4-carbohydrazide的分子式是什么？
(E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(3-bromobenzylidene)-5-((4-methylpiperazin-1-yl)methyl)-1H-1,2,3-triazole-4-carbohydrazide的分子式为C18H21BrN10O2。
(E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(3-bromobenzylidene)-5-((4-methylpiperazin-1-yl)methyl)-1H-1,2,3-triazole-4-carbohydrazide的分子量是多少？
(E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(3-bromobenzylidene)-5-((4-methylpiperazin-1-yl)methyl)-1H-1,2,3-triazole-4-carbohydrazide的分子量为488.10 g/mol。
在哪里可以购买(E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(3-bromobenzylidene)-5-((4-methylpiperazin-1-yl)methyl)-1H-1,2,3-triazole-4-carbohydrazide？
您可以直接向科弘生物询价(E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(3-bromobenzylidene)-5-((4-methylpiperazin-1-yl)methyl)-1H-1,2,3-triazole-4-carbohydrazide。联系我们或发送邮件至info@kehongbio.com获取报价和库存信息。
科弘生物是否提供(E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(3-bromobenzylidene)-5-((4-methylpiperazin-1-yl)methyl)-1H-1,2,3-triazole-4-carbohydrazide的定制合成服务？
是的，科弘生物提供(E)-1-(4-amino-1,2,5-oxadiazol-3-yl)-N'-(3-bromobenzylidene)-5-((4-methylpiperazin-1-yl)methyl)-1H-1,2,3-triazole-4-carbohydrazide及相关化合物的定制合成服务。请联系我们并告知您的具体需求，包括数量、纯度和交期。