![2-[4-(4-chlorobenzyl)piperazin-1-yl]-N'-[(1E)-1-phenylethylidene]acetohydrazide structure](/static/products/489/489415-53-4.png)
2-[4-(4-chlorobenzyl)piperazin-1-yl]-N'-[(1E)-1-phenylethylidene]acetohydrazide
TL;DR: 2-[4-(4-chlorobenzyl)piperazin-1-yl]-N'-[(1E)-1-phenylethylidene]acetohydrazide (CAS 489415-53-4) is a chemical compound with molecular formula C21H25ClN4O and molecular weight 384.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[4-[(4-chlorophenyl)methyl]piperazin-1-yl]-N-[(E)-1-phenylethylideneamino]acetamide
Also Known As: (E)-2-(4-(4-chlorobenzyl)piperazin-1-yl)-N'-(1-phenylethylidene)acetohydrazide, 2-[4-(4-chlorobenzyl)piperazin-1-yl]-N'-[(1E)-1-phenylethylidene]acetohydrazide, 2-[4-[(4-chlorophenyl)methyl]piperazin-1-yl]-N-(1-phenylethylideneamino)acetamide, N-((1E)-2-phenyl-1-azaprop-1-enyl)-2-{4-[(4-chlorophenyl)methyl]piperazinyl}ac etamide
| Molecular Formula | C21H25ClN4O |
|---|---|
| Molecular Weight | 384.17 g/mol |
| LogP | 2.998 |
| Topological Polar Surface Area | 47.94 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 6 |
| Exact Mass | 384.1717 |
| Heavy Atoms | 27 |
| Complexity | 768.52844 |
Chemical Identifiers
| CAS Number | 489415-53-4 |
|---|---|
| SMILES | C/C(=N\NC(=O)CN1CCN(CC1)CC2=CC=C(C=C2)Cl)/C3=CC=CC=C3 |
Product Overview
2-[4-(4-chlorobenzyl)piperazin-1-yl]-N'-[(1E)-1-phenylethylidene]acetohydrazide (CAS 489415-53-4), with molecular formula C21H25ClN4O and molecular weight 384.17 g/mol. IUPAC: 2-[4-[(4-chlorophenyl)methyl]piperazin-1-yl]-N-[(E)-1-phenylethylideneamino]acetamide.
Chemical Property Profile of 2-[4-(4-chlorobenzyl)piperazin-1-yl]-N'-[(1E)-1-phenylethylidene]acetohydrazide
Property Insights of 2-[4-(4-chlorobenzyl)piperazin-1-yl]-N'-[(1E)-1-phenylethylidene]acetohydrazide
The XLogP value of 2.998 suggests moderate lipophilicity, balancing water solubility and membrane permeability for 2-[4-(4-chlorobenzyl)piperazin-1-yl]-N'-[(1E)-1-phenylethylidene]acetohydrazide. With a topological polar surface area (TPSA) of 47.94 Ų, 2-[4-(4-chlorobenzyl)piperazin-1-yl]-N'-[(1E)-1-phenylethylidene]acetohydrazide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 2-[4-(4-chlorobenzyl)piperazin-1-yl]-N'-[(1E)-1-phenylethylidene]acetohydrazide has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 2-[4-(4-chlorobenzyl)piperazin-1-yl]-N'-[(1E)-1-phenylethylidene]acetohydrazide?
The CAS number of 2-[4-(4-chlorobenzyl)piperazin-1-yl]-N'-[(1E)-1-phenylethylidene]acetohydrazide is 489415-53-4.
What is the molecular formula of 2-[4-(4-chlorobenzyl)piperazin-1-yl]-N'-[(1E)-1-phenylethylidene]acetohydrazide?
The molecular formula of 2-[4-(4-chlorobenzyl)piperazin-1-yl]-N'-[(1E)-1-phenylethylidene]acetohydrazide is C21H25ClN4O.
What is the molecular weight of 2-[4-(4-chlorobenzyl)piperazin-1-yl]-N'-[(1E)-1-phenylethylidene]acetohydrazide?
The molecular weight of 2-[4-(4-chlorobenzyl)piperazin-1-yl]-N'-[(1E)-1-phenylethylidene]acetohydrazide is 384.17 g/mol.
Where can I buy 2-[4-(4-chlorobenzyl)piperazin-1-yl]-N'-[(1E)-1-phenylethylidene]acetohydrazide?
You can request a quote for 2-[4-(4-chlorobenzyl)piperazin-1-yl]-N'-[(1E)-1-phenylethylidene]acetohydrazide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 2-[4-(4-chlorobenzyl)piperazin-1-yl]-N'-[(1E)-1-phenylethylidene]acetohydrazide?
Yes, KEHONG BIO provides custom synthesis services for 2-[4-(4-chlorobenzyl)piperazin-1-yl]-N'-[(1E)-1-phenylethylidene]acetohydrazide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.