(E)-2-(4-(4-methylbenzyl)piperazin-1-yl)-N'-(1-(pyridin-4-yl)ethylidene)acetohydrazide
TL;DR: (E)-2-(4-(4-methylbenzyl)piperazin-1-yl)-N'-(1-(pyridin-4-yl)ethylidene)acetohydrazide (CAS 489414-35-9) is a chemical compound with molecular formula C21H27N5O and molecular weight 365.22 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[4-[(4-methylphenyl)methyl]piperazin-1-yl]-N-[(E)-1-pyridin-4-ylethylideneamino]acetamide
Also Known As: (E)-2-(4-(4-methylbenzyl)piperazin-1-yl)-N'-(1-(pyridin-4-yl)ethylidene)acetohydrazide, 2-[4-(4-methylbenzyl)piperazin-1-yl]-N'-[(1E)-1-(pyridin-4-yl)ethylidene]acetohydrazide, [4-(4-Methyl-benzyl)-piperazin-1-yl]-acetic acid [1-pyridin-4-yl-eth-(E)-ylidene]-hydrazide, 2-[4-[(4-methylphenyl)methyl]piperazin-1-yl]-N-[(E)-1-pyridin-4-ylethylideneamino]acetamide, N-((1E)-2-(4-pyridyl)-1-azaprop-1-enyl)-2-{4-[(4-methylphenyl)methyl]piperazin yl}acetamide
| Molecular Formula | C21H27N5O |
|---|---|
| Molecular Weight | 365.22 g/mol |
| LogP | 2.04802 |
| Topological Polar Surface Area | 60.83 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Exact Mass | 365.22156 |
| Heavy Atoms | 27 |
| Complexity | 764.9188 |
Chemical Identifiers
| CAS Number | 489414-35-9 |
|---|---|
| SMILES | CC1=CC=C(C=C1)CN2CCN(CC2)CC(=O)N/N=C(\C)/C3=CC=NC=C3 |
Product Overview
(E)-2-(4-(4-methylbenzyl)piperazin-1-yl)-N'-(1-(pyridin-4-yl)ethylidene)acetohydrazide (CAS 489414-35-9), with molecular formula C21H27N5O and molecular weight 365.22 g/mol. IUPAC: 2-[4-[(4-methylphenyl)methyl]piperazin-1-yl]-N-[(E)-1-pyridin-4-ylethylideneamino]acetamide.
Chemical Property Profile of (E)-2-(4-(4-methylbenzyl)piperazin-1-yl)-N'-(1-(pyridin-4-yl)ethylidene)acetohydrazide
Property Insights of (E)-2-(4-(4-methylbenzyl)piperazin-1-yl)-N'-(1-(pyridin-4-yl)ethylidene)acetohydrazide
The XLogP value of 2.04802 suggests moderate lipophilicity, balancing water solubility and membrane permeability for (E)-2-(4-(4-methylbenzyl)piperazin-1-yl)-N'-(1-(pyridin-4-yl)ethylidene)acetohydrazide. The TPSA of 60.83 Ų falls within the moderate polarity range, balancing permeability and solubility for (E)-2-(4-(4-methylbenzyl)piperazin-1-yl)-N'-(1-(pyridin-4-yl)ethylidene)acetohydrazide. Following Lipinski's Rule of Five, (E)-2-(4-(4-methylbenzyl)piperazin-1-yl)-N'-(1-(pyridin-4-yl)ethylidene)acetohydrazide has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-2-(4-(4-methylbenzyl)piperazin-1-yl)-N'-(1-(pyridin-4-yl)ethylidene)acetohydrazide?
The CAS number of (E)-2-(4-(4-methylbenzyl)piperazin-1-yl)-N'-(1-(pyridin-4-yl)ethylidene)acetohydrazide is 489414-35-9.
What is the molecular formula of (E)-2-(4-(4-methylbenzyl)piperazin-1-yl)-N'-(1-(pyridin-4-yl)ethylidene)acetohydrazide?
The molecular formula of (E)-2-(4-(4-methylbenzyl)piperazin-1-yl)-N'-(1-(pyridin-4-yl)ethylidene)acetohydrazide is C21H27N5O.
What is the molecular weight of (E)-2-(4-(4-methylbenzyl)piperazin-1-yl)-N'-(1-(pyridin-4-yl)ethylidene)acetohydrazide?
The molecular weight of (E)-2-(4-(4-methylbenzyl)piperazin-1-yl)-N'-(1-(pyridin-4-yl)ethylidene)acetohydrazide is 365.22 g/mol.
Where can I buy (E)-2-(4-(4-methylbenzyl)piperazin-1-yl)-N'-(1-(pyridin-4-yl)ethylidene)acetohydrazide?
You can request a quote for (E)-2-(4-(4-methylbenzyl)piperazin-1-yl)-N'-(1-(pyridin-4-yl)ethylidene)acetohydrazide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-2-(4-(4-methylbenzyl)piperazin-1-yl)-N'-(1-(pyridin-4-yl)ethylidene)acetohydrazide?
Yes, KEHONG BIO provides custom synthesis services for (E)-2-(4-(4-methylbenzyl)piperazin-1-yl)-N'-(1-(pyridin-4-yl)ethylidene)acetohydrazide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.