6-(4-Chlorophenyl)-3-(4-fluorophenyl)-5-(4-methylpiperazin-1-yl)-1,2,4-triazine
TL;DR: 6-(4-Chlorophenyl)-3-(4-fluorophenyl)-5-(4-methylpiperazin-1-yl)-1,2,4-triazine (CAS 489411-72-5) is a chemical compound with molecular formula C20H19ClFN5 and molecular weight 383.13 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6-(4-chlorophenyl)-3-(4-fluorophenyl)-5-(4-methylpiperazin-1-yl)-1,2,4-triazine
Also Known As: 6-(4-chlorophenyl)-3-(4-fluorophenyl)-5-(4-methylpiperazin-1-yl)-1,2,4-triazine
| Molecular Formula | C20H19ClFN5 |
|---|---|
| Molecular Weight | 383.13 g/mol |
| LogP | 3.7499 |
| Topological Polar Surface Area | 45.15 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 3 |
| Exact Mass | 383.1313 |
| Heavy Atoms | 27 |
| Complexity | 922.10706 |
Chemical Identifiers
| CAS Number | 489411-72-5 |
|---|---|
| SMILES | CN1CCN(CC1)C2=C(N=NC(=N2)C3=CC=C(C=C3)F)C4=CC=C(C=C4)Cl |
Product Overview
6-(4-Chlorophenyl)-3-(4-fluorophenyl)-5-(4-methylpiperazin-1-yl)-1,2,4-triazine (CAS 489411-72-5), with molecular formula C20H19ClFN5 and molecular weight 383.13 g/mol. IUPAC: 6-(4-chlorophenyl)-3-(4-fluorophenyl)-5-(4-methylpiperazin-1-yl)-1,2,4-triazine.
Chemical Property Profile of 6-(4-Chlorophenyl)-3-(4-fluorophenyl)-5-(4-methylpiperazin-1-yl)-1,2,4-triazine
Property Insights of 6-(4-Chlorophenyl)-3-(4-fluorophenyl)-5-(4-methylpiperazin-1-yl)-1,2,4-triazine
The XLogP value of 3.7499 indicates that 6-(4-Chlorophenyl)-3-(4-fluorophenyl)-5-(4-methylpiperazin-1-yl)-1,2,4-triazine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 45.15 Ų, 6-(4-Chlorophenyl)-3-(4-fluorophenyl)-5-(4-methylpiperazin-1-yl)-1,2,4-triazine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 6-(4-Chlorophenyl)-3-(4-fluorophenyl)-5-(4-methylpiperazin-1-yl)-1,2,4-triazine has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 6-(4-Chlorophenyl)-3-(4-fluorophenyl)-5-(4-methylpiperazin-1-yl)-1,2,4-triazine?
The CAS number of 6-(4-Chlorophenyl)-3-(4-fluorophenyl)-5-(4-methylpiperazin-1-yl)-1,2,4-triazine is 489411-72-5.
What is the molecular formula of 6-(4-Chlorophenyl)-3-(4-fluorophenyl)-5-(4-methylpiperazin-1-yl)-1,2,4-triazine?
The molecular formula of 6-(4-Chlorophenyl)-3-(4-fluorophenyl)-5-(4-methylpiperazin-1-yl)-1,2,4-triazine is C20H19ClFN5.
What is the molecular weight of 6-(4-Chlorophenyl)-3-(4-fluorophenyl)-5-(4-methylpiperazin-1-yl)-1,2,4-triazine?
The molecular weight of 6-(4-Chlorophenyl)-3-(4-fluorophenyl)-5-(4-methylpiperazin-1-yl)-1,2,4-triazine is 383.13 g/mol.
Where can I buy 6-(4-Chlorophenyl)-3-(4-fluorophenyl)-5-(4-methylpiperazin-1-yl)-1,2,4-triazine?
You can request a quote for 6-(4-Chlorophenyl)-3-(4-fluorophenyl)-5-(4-methylpiperazin-1-yl)-1,2,4-triazine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 6-(4-Chlorophenyl)-3-(4-fluorophenyl)-5-(4-methylpiperazin-1-yl)-1,2,4-triazine?
Yes, KEHONG BIO provides custom synthesis services for 6-(4-Chlorophenyl)-3-(4-fluorophenyl)-5-(4-methylpiperazin-1-yl)-1,2,4-triazine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.