5-(4-bromophenyl)-4-cinnamoyl-3-hydroxy-1-(3-(trifluoromethyl)phenyl)-1H-pyrrol-2(5H)-one
TL;DR: 5-(4-bromophenyl)-4-cinnamoyl-3-hydroxy-1-(3-(trifluoromethyl)phenyl)-1H-pyrrol-2(5H)-one (CAS 489404-59-3) is a chemical compound with molecular formula C26H17BrF3NO3 and molecular weight 527.03 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-(4-bromophenyl)-4-hydroxy-3-[(E)-3-phenylprop-2-enoyl]-1-[3-(trifluoromethyl)phenyl]-2H-pyrrol-5-one
Also Known As: 5-(4-bromophenyl)-4-cinnamoyl-3-hydroxy-1-(3-(trifluoromethyl)phenyl)-1H-pyrrol-2(5H)-one, 2-(4-bromophenyl)-4-hydroxy-3-[(E)-3-phenylprop-2-enoyl]-1-[3-(trifluoromethyl)phenyl]-2H-pyrrol-5-one, 5-(4-bromophenyl)-3-hydroxy-4-(3-phenylprop-2-enoyl)-1-[3-(trifluoromethyl)phenyl]-5H-pyrrol-2-one, 5-(4-bromophenyl)-3-hydroxy-4-[(2E)-3-phenylprop-2-enoyl]-1-[3-(trifluoromethyl)phenyl]-1,5-dihydro-2H-pyrrol-2-one
| Molecular Formula | C26H17BrF3NO3 |
|---|---|
| Molecular Weight | 527.03 g/mol |
| LogP | 6.6504 |
| Topological Polar Surface Area | 57.61 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 5 |
| Exact Mass | 527.03436 |
| Heavy Atoms | 34 |
| Complexity | 1298.8711 |
Chemical Identifiers
| CAS Number | 489404-59-3 |
|---|---|
| SMILES | C1=CC=C(C=C1)/C=C/C(=O)C2=C(C(=O)N(C2C3=CC=C(C=C3)Br)C4=CC=CC(=C4)C(F)(F)F)O |
Product Overview
5-(4-bromophenyl)-4-cinnamoyl-3-hydroxy-1-(3-(trifluoromethyl)phenyl)-1H-pyrrol-2(5H)-one (CAS 489404-59-3), with molecular formula C26H17BrF3NO3 and molecular weight 527.03 g/mol. IUPAC: 2-(4-bromophenyl)-4-hydroxy-3-[(E)-3-phenylprop-2-enoyl]-1-[3-(trifluoromethyl)phenyl]-2H-pyrrol-5-one.
Chemical Property Profile of 5-(4-bromophenyl)-4-cinnamoyl-3-hydroxy-1-(3-(trifluoromethyl)phenyl)-1H-pyrrol-2(5H)-one
Property Insights of 5-(4-bromophenyl)-4-cinnamoyl-3-hydroxy-1-(3-(trifluoromethyl)phenyl)-1H-pyrrol-2(5H)-one
The XLogP value of 6.6504 indicates that 5-(4-bromophenyl)-4-cinnamoyl-3-hydroxy-1-(3-(trifluoromethyl)phenyl)-1H-pyrrol-2(5H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 57.61 Ų, 5-(4-bromophenyl)-4-cinnamoyl-3-hydroxy-1-(3-(trifluoromethyl)phenyl)-1H-pyrrol-2(5H)-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 5-(4-bromophenyl)-4-cinnamoyl-3-hydroxy-1-(3-(trifluoromethyl)phenyl)-1H-pyrrol-2(5H)-one has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-(4-bromophenyl)-4-cinnamoyl-3-hydroxy-1-(3-(trifluoromethyl)phenyl)-1H-pyrrol-2(5H)-one?
The CAS number of 5-(4-bromophenyl)-4-cinnamoyl-3-hydroxy-1-(3-(trifluoromethyl)phenyl)-1H-pyrrol-2(5H)-one is 489404-59-3.
What is the molecular formula of 5-(4-bromophenyl)-4-cinnamoyl-3-hydroxy-1-(3-(trifluoromethyl)phenyl)-1H-pyrrol-2(5H)-one?
The molecular formula of 5-(4-bromophenyl)-4-cinnamoyl-3-hydroxy-1-(3-(trifluoromethyl)phenyl)-1H-pyrrol-2(5H)-one is C26H17BrF3NO3.
What is the molecular weight of 5-(4-bromophenyl)-4-cinnamoyl-3-hydroxy-1-(3-(trifluoromethyl)phenyl)-1H-pyrrol-2(5H)-one?
The molecular weight of 5-(4-bromophenyl)-4-cinnamoyl-3-hydroxy-1-(3-(trifluoromethyl)phenyl)-1H-pyrrol-2(5H)-one is 527.03 g/mol.
Where can I buy 5-(4-bromophenyl)-4-cinnamoyl-3-hydroxy-1-(3-(trifluoromethyl)phenyl)-1H-pyrrol-2(5H)-one?
You can request a quote for 5-(4-bromophenyl)-4-cinnamoyl-3-hydroxy-1-(3-(trifluoromethyl)phenyl)-1H-pyrrol-2(5H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-(4-bromophenyl)-4-cinnamoyl-3-hydroxy-1-(3-(trifluoromethyl)phenyl)-1H-pyrrol-2(5H)-one?
Yes, KEHONG BIO provides custom synthesis services for 5-(4-bromophenyl)-4-cinnamoyl-3-hydroxy-1-(3-(trifluoromethyl)phenyl)-1H-pyrrol-2(5H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.