(4E)-5-(4-bromophenyl)-4-(1-hydroxyethylidene)-1-phenylpyrrolidine-2,3-dione
TL;DR: (4E)-5-(4-bromophenyl)-4-(1-hydroxyethylidene)-1-phenylpyrrolidine-2,3-dione (CAS 489398-84-7) is a chemical compound with molecular formula C18H14BrNO3 and molecular weight 371.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-acetyl-2-(4-bromophenyl)-4-hydroxy-1-phenyl-2H-pyrrol-5-one
Also Known As: 3-acetyl-2-(4-bromophenyl)-4-hydroxy-1-phenyl-2H-pyrrol-5-one, 4-acetyl-5-(4-bromophenyl)-3-hydroxy-1-phenyl-1H-pyrrol-2(5H)-one, (4E)-5-(4-bromophenyl)-4-(1-hydroxyethylidene)-1-phenylpyrrolidine-2,3-dione
| Molecular Formula | C18H14BrNO3 |
|---|---|
| Molecular Weight | 371.02 g/mol |
| LogP | 3.9381 |
| Topological Polar Surface Area | 57.61 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 3 |
| Exact Mass | 371.01572 |
| Heavy Atoms | 23 |
| Complexity | 796.77625 |
Chemical Identifiers
| CAS Number | 489398-84-7 |
|---|---|
| SMILES | CC(=O)C1=C(C(=O)N(C1C2=CC=C(C=C2)Br)C3=CC=CC=C3)O |
Product Overview
(4E)-5-(4-bromophenyl)-4-(1-hydroxyethylidene)-1-phenylpyrrolidine-2,3-dione (CAS 489398-84-7), with molecular formula C18H14BrNO3 and molecular weight 371.02 g/mol. IUPAC: 3-acetyl-2-(4-bromophenyl)-4-hydroxy-1-phenyl-2H-pyrrol-5-one.
Chemical Property Profile of (4E)-5-(4-bromophenyl)-4-(1-hydroxyethylidene)-1-phenylpyrrolidine-2,3-dione
Property Insights of (4E)-5-(4-bromophenyl)-4-(1-hydroxyethylidene)-1-phenylpyrrolidine-2,3-dione
The XLogP value of 3.9381 indicates that (4E)-5-(4-bromophenyl)-4-(1-hydroxyethylidene)-1-phenylpyrrolidine-2,3-dione is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 57.61 Ų, (4E)-5-(4-bromophenyl)-4-(1-hydroxyethylidene)-1-phenylpyrrolidine-2,3-dione exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (4E)-5-(4-bromophenyl)-4-(1-hydroxyethylidene)-1-phenylpyrrolidine-2,3-dione has 1 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (4E)-5-(4-bromophenyl)-4-(1-hydroxyethylidene)-1-phenylpyrrolidine-2,3-dione?
The CAS number of (4E)-5-(4-bromophenyl)-4-(1-hydroxyethylidene)-1-phenylpyrrolidine-2,3-dione is 489398-84-7.
What is the molecular formula of (4E)-5-(4-bromophenyl)-4-(1-hydroxyethylidene)-1-phenylpyrrolidine-2,3-dione?
The molecular formula of (4E)-5-(4-bromophenyl)-4-(1-hydroxyethylidene)-1-phenylpyrrolidine-2,3-dione is C18H14BrNO3.
What is the molecular weight of (4E)-5-(4-bromophenyl)-4-(1-hydroxyethylidene)-1-phenylpyrrolidine-2,3-dione?
The molecular weight of (4E)-5-(4-bromophenyl)-4-(1-hydroxyethylidene)-1-phenylpyrrolidine-2,3-dione is 371.02 g/mol.
Where can I buy (4E)-5-(4-bromophenyl)-4-(1-hydroxyethylidene)-1-phenylpyrrolidine-2,3-dione?
You can request a quote for (4E)-5-(4-bromophenyl)-4-(1-hydroxyethylidene)-1-phenylpyrrolidine-2,3-dione directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (4E)-5-(4-bromophenyl)-4-(1-hydroxyethylidene)-1-phenylpyrrolidine-2,3-dione?
Yes, KEHONG BIO provides custom synthesis services for (4E)-5-(4-bromophenyl)-4-(1-hydroxyethylidene)-1-phenylpyrrolidine-2,3-dione and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.