(Z)-N'-(1-(3,4-dimethoxyphenyl)ethylidene)-2-((4-oxo-3-(p-tolyl)-3,4-dihydroquinazolin-2-yl)thio)acetohydrazide structure

(Z)-N'-(1-(3,4-dimethoxyphenyl)ethylidene)-2-((4-oxo-3-(p-tolyl)-3,4-dihydroquinazolin-2-yl)thio)acetohydrazide

TL;DR: (Z)-N'-(1-(3,4-dimethoxyphenyl)ethylidene)-2-((4-oxo-3-(p-tolyl)-3,4-dihydroquinazolin-2-yl)thio)acetohydrazide (CAS 489396-53-4) is a chemical compound with molecular formula C27H26N4O4S and molecular weight 502.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

N-[(Z)-1-(3,4-dimethoxyphenyl)ethylideneamino]-2-[3-(4-methylphenyl)-4-oxoquinazolin-2-yl]sulfanylacetamide

Also Known As: (Z)-N'-(1-(3,4-dimethoxyphenyl)ethylidene)-2-((4-oxo-3-(p-tolyl)-3,4-dihydroquinazolin-2-yl)thio)acetohydrazide, N'-[(1Z)-1-(3,4-dimethoxyphenyl)ethylidene]-2-{[3-(4-methylphenyl)-4-oxo-3,4-dihydroquinazolin-2-yl]sulfanyl}acetohydrazide, N-[(1Z)-2-(3,4-dimethoxyphenyl)-1-azaprop-1-enyl]-2-[3-(4-methylphenyl)-4-oxo( 3-hydroquinazolin-2-ylthio)]acetamide, N-[(Z)-1-(3,4-dimethoxyphenyl)ethylideneamino]-2-[3-(4-methylphenyl)-4-oxoquinazolin-2-yl]sulfanylacetamide

CAS: 489396-53-4
Molecular Formula C27H26N4O4S
Molecular Weight 502.17 g/mol
LogP 4.34382
Topological Polar Surface Area 94.81 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 7
Rotatable Bonds 8
Exact Mass 502.16748
Heavy Atoms 36
Complexity 1496.4235

Chemical Identifiers

CAS Number 489396-53-4
SMILES CC1=CC=C(C=C1)N2C(=O)C3=CC=CC=C3N=C2SCC(=O)N/N=C(/C)\C4=CC(=C(C=C4)OC)OC

Product Overview

(Z)-N'-(1-(3,4-dimethoxyphenyl)ethylidene)-2-((4-oxo-3-(p-tolyl)-3,4-dihydroquinazolin-2-yl)thio)acetohydrazide (CAS 489396-53-4), with molecular formula C27H26N4O4S and molecular weight 502.17 g/mol. IUPAC: N-[(Z)-1-(3,4-dimethoxyphenyl)ethylideneamino]-2-[3-(4-methylphenyl)-4-oxoquinazolin-2-yl]sulfanylacetamide.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of (Z)-N'-(1-(3,4-dimethoxyphenyl)ethylidene)-2-((4-oxo-3-(p-tolyl)-3,4-dihydroquinazolin-2-yl)thio)acetohydrazide

XLogP
4.34382
TPSA (Topological Polar Surface Area)
94.81
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
7
Rotatable Bonds
8
Heavy Atoms
36
Complexity
1496.4235
Exact Mass
502.16748
Monoisotopic Mass
502.16748
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of (Z)-N'-(1-(3,4-dimethoxyphenyl)ethylidene)-2-((4-oxo-3-(p-tolyl)-3,4-dihydroquinazolin-2-yl)thio)acetohydrazide

The XLogP value of 4.34382 indicates that (Z)-N'-(1-(3,4-dimethoxyphenyl)ethylidene)-2-((4-oxo-3-(p-tolyl)-3,4-dihydroquinazolin-2-yl)thio)acetohydrazide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 94.81 Ų falls within the moderate polarity range, balancing permeability and solubility for (Z)-N'-(1-(3,4-dimethoxyphenyl)ethylidene)-2-((4-oxo-3-(p-tolyl)-3,4-dihydroquinazolin-2-yl)thio)acetohydrazide. Following Lipinski's Rule of Five, (Z)-N'-(1-(3,4-dimethoxyphenyl)ethylidene)-2-((4-oxo-3-(p-tolyl)-3,4-dihydroquinazolin-2-yl)thio)acetohydrazide has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of (Z)-N'-(1-(3,4-dimethoxyphenyl)ethylidene)-2-((4-oxo-3-(p-tolyl)-3,4-dihydroquinazolin-2-yl)thio)acetohydrazide?

The CAS number of (Z)-N'-(1-(3,4-dimethoxyphenyl)ethylidene)-2-((4-oxo-3-(p-tolyl)-3,4-dihydroquinazolin-2-yl)thio)acetohydrazide is 489396-53-4.

What is the molecular formula of (Z)-N'-(1-(3,4-dimethoxyphenyl)ethylidene)-2-((4-oxo-3-(p-tolyl)-3,4-dihydroquinazolin-2-yl)thio)acetohydrazide?

The molecular formula of (Z)-N'-(1-(3,4-dimethoxyphenyl)ethylidene)-2-((4-oxo-3-(p-tolyl)-3,4-dihydroquinazolin-2-yl)thio)acetohydrazide is C27H26N4O4S.

What is the molecular weight of (Z)-N'-(1-(3,4-dimethoxyphenyl)ethylidene)-2-((4-oxo-3-(p-tolyl)-3,4-dihydroquinazolin-2-yl)thio)acetohydrazide?

The molecular weight of (Z)-N'-(1-(3,4-dimethoxyphenyl)ethylidene)-2-((4-oxo-3-(p-tolyl)-3,4-dihydroquinazolin-2-yl)thio)acetohydrazide is 502.17 g/mol.

Where can I buy (Z)-N'-(1-(3,4-dimethoxyphenyl)ethylidene)-2-((4-oxo-3-(p-tolyl)-3,4-dihydroquinazolin-2-yl)thio)acetohydrazide?

You can request a quote for (Z)-N'-(1-(3,4-dimethoxyphenyl)ethylidene)-2-((4-oxo-3-(p-tolyl)-3,4-dihydroquinazolin-2-yl)thio)acetohydrazide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for (Z)-N'-(1-(3,4-dimethoxyphenyl)ethylidene)-2-((4-oxo-3-(p-tolyl)-3,4-dihydroquinazolin-2-yl)thio)acetohydrazide?

Yes, KEHONG BIO provides custom synthesis services for (Z)-N'-(1-(3,4-dimethoxyphenyl)ethylidene)-2-((4-oxo-3-(p-tolyl)-3,4-dihydroquinazolin-2-yl)thio)acetohydrazide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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