1-(3-Chlorobenzoyl)-4-(2-fluorobenzoyl)piperazine
TL;DR: 1-(3-Chlorobenzoyl)-4-(2-fluorobenzoyl)piperazine (CAS 488797-20-2) is a chemical compound with molecular formula C18H16ClFN2O2 and molecular weight 346.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(3-chlorophenyl)-[4-(2-fluorobenzoyl)piperazin-1-yl]methanone
Also Known As: 1-(3-chlorobenzoyl)-4-(2-fluorobenzoyl)piperazine, AN-153/43309854, (3-chlorophenyl)-[4-(2-fluorobenzoyl)piperazin-1-yl]methanone, (3-chlorophenyl){4-[(2-fluorophenyl)carbonyl]piperazin-1-yl}methanone, (4-(3-chlorobenzoyl)piperazin-1-yl)(2-fluorophenyl)methanone
| Molecular Formula | C18H16ClFN2O2 |
|---|---|
| Molecular Weight | 346.09 g/mol |
| LogP | 3.0 |
| Topological Polar Surface Area | 40.6 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 346.08844 |
| Heavy Atoms | 24 |
| Complexity | 468.0 |
Chemical Identifiers
| CAS Number | 488797-20-2 |
|---|---|
| SMILES | C1CN(CCN1C(=O)C2=CC(=CC=C2)Cl)C(=O)C3=CC=CC=C3F |
| InChIKey | OZLVYKOACIKHAZ-UHFFFAOYSA-N |
Product Overview
1-(3-Chlorobenzoyl)-4-(2-fluorobenzoyl)piperazine (CAS 488797-20-2), with molecular formula C18H16ClFN2O2 and molecular weight 346.09 g/mol. IUPAC: (3-chlorophenyl)-[4-(2-fluorobenzoyl)piperazin-1-yl]methanone.
Chemical Property Profile of 1-(3-Chlorobenzoyl)-4-(2-fluorobenzoyl)piperazine
Property Insights of 1-(3-Chlorobenzoyl)-4-(2-fluorobenzoyl)piperazine
The XLogP value of 3.0 indicates that 1-(3-Chlorobenzoyl)-4-(2-fluorobenzoyl)piperazine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 40.6 Ų, 1-(3-Chlorobenzoyl)-4-(2-fluorobenzoyl)piperazine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 1-(3-Chlorobenzoyl)-4-(2-fluorobenzoyl)piperazine has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-(3-Chlorobenzoyl)-4-(2-fluorobenzoyl)piperazine?
The CAS number of 1-(3-Chlorobenzoyl)-4-(2-fluorobenzoyl)piperazine is 488797-20-2.
What is the molecular formula of 1-(3-Chlorobenzoyl)-4-(2-fluorobenzoyl)piperazine?
The molecular formula of 1-(3-Chlorobenzoyl)-4-(2-fluorobenzoyl)piperazine is C18H16ClFN2O2.
What is the molecular weight of 1-(3-Chlorobenzoyl)-4-(2-fluorobenzoyl)piperazine?
The molecular weight of 1-(3-Chlorobenzoyl)-4-(2-fluorobenzoyl)piperazine is 346.09 g/mol.
Where can I buy 1-(3-Chlorobenzoyl)-4-(2-fluorobenzoyl)piperazine?
You can request a quote for 1-(3-Chlorobenzoyl)-4-(2-fluorobenzoyl)piperazine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-(3-Chlorobenzoyl)-4-(2-fluorobenzoyl)piperazine?
Yes, KEHONG BIO provides custom synthesis services for 1-(3-Chlorobenzoyl)-4-(2-fluorobenzoyl)piperazine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.