(E)-2-((5-(4-methoxyphenyl)-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)-N'-(1-phenylethylidene)acetohydrazide
TL;DR: (E)-2-((5-(4-methoxyphenyl)-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)-N'-(1-phenylethylidene)acetohydrazide (CAS 488795-05-7) is a chemical compound with molecular formula C26H25N5O2S and molecular weight 471.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[[5-(4-methoxyphenyl)-4-(4-methylphenyl)-1,2,4-triazol-3-yl]sulfanyl]-N-[(E)-1-phenylethylideneamino]acetamide
Also Known As: (E)-2-((5-(4-methoxyphenyl)-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)-N'-(1-phenylethylidene)acetohydrazide, 2-[[5-(4-methoxyphenyl)-4-(4-methylphenyl)-1,2,4-triazol-3-yl]sulfanyl]-N-[(E)-1-phenylethylideneamino]acetamide, 2-{[5-(4-methoxyphenyl)-4-(4-methylphenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}-N'-[(E)-1-phenylethylidene]acetohydrazide
| Molecular Formula | C26H25N5O2S |
|---|---|
| Molecular Weight | 471.17 g/mol |
| LogP | 4.88382 |
| Topological Polar Surface Area | 81.4 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 8 |
| Exact Mass | 471.17288 |
| Heavy Atoms | 34 |
| Complexity | 1283.2877 |
Chemical Identifiers
| CAS Number | 488795-05-7 |
|---|---|
| SMILES | CC1=CC=C(C=C1)N2C(=NN=C2SCC(=O)N/N=C(\C)/C3=CC=CC=C3)C4=CC=C(C=C4)OC |
Product Overview
(E)-2-((5-(4-methoxyphenyl)-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)-N'-(1-phenylethylidene)acetohydrazide (CAS 488795-05-7), with molecular formula C26H25N5O2S and molecular weight 471.17 g/mol. IUPAC: 2-[[5-(4-methoxyphenyl)-4-(4-methylphenyl)-1,2,4-triazol-3-yl]sulfanyl]-N-[(E)-1-phenylethylideneamino]acetamide.
Chemical Property Profile of (E)-2-((5-(4-methoxyphenyl)-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)-N'-(1-phenylethylidene)acetohydrazide
Property Insights of (E)-2-((5-(4-methoxyphenyl)-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)-N'-(1-phenylethylidene)acetohydrazide
The XLogP value of 4.88382 indicates that (E)-2-((5-(4-methoxyphenyl)-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)-N'-(1-phenylethylidene)acetohydrazide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 81.4 Ų falls within the moderate polarity range, balancing permeability and solubility for (E)-2-((5-(4-methoxyphenyl)-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)-N'-(1-phenylethylidene)acetohydrazide. Following Lipinski's Rule of Five, (E)-2-((5-(4-methoxyphenyl)-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)-N'-(1-phenylethylidene)acetohydrazide has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-2-((5-(4-methoxyphenyl)-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)-N'-(1-phenylethylidene)acetohydrazide?
The CAS number of (E)-2-((5-(4-methoxyphenyl)-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)-N'-(1-phenylethylidene)acetohydrazide is 488795-05-7.
What is the molecular formula of (E)-2-((5-(4-methoxyphenyl)-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)-N'-(1-phenylethylidene)acetohydrazide?
The molecular formula of (E)-2-((5-(4-methoxyphenyl)-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)-N'-(1-phenylethylidene)acetohydrazide is C26H25N5O2S.
What is the molecular weight of (E)-2-((5-(4-methoxyphenyl)-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)-N'-(1-phenylethylidene)acetohydrazide?
The molecular weight of (E)-2-((5-(4-methoxyphenyl)-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)-N'-(1-phenylethylidene)acetohydrazide is 471.17 g/mol.
Where can I buy (E)-2-((5-(4-methoxyphenyl)-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)-N'-(1-phenylethylidene)acetohydrazide?
You can request a quote for (E)-2-((5-(4-methoxyphenyl)-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)-N'-(1-phenylethylidene)acetohydrazide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-2-((5-(4-methoxyphenyl)-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)-N'-(1-phenylethylidene)acetohydrazide?
Yes, KEHONG BIO provides custom synthesis services for (E)-2-((5-(4-methoxyphenyl)-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)-N'-(1-phenylethylidene)acetohydrazide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.