(E)-N'-((5-(4-((difluoromethyl)thio)phenyl)furan-2-yl)methylene)isonicotinohydrazide
TL;DR: (E)-N'-((5-(4-((difluoromethyl)thio)phenyl)furan-2-yl)methylene)isonicotinohydrazide (CAS 488793-69-7) is a chemical compound with molecular formula C18H13F2N3O2S and molecular weight 373.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[(E)-[5-[4-(difluoromethylsulfanyl)phenyl]furan-2-yl]methylideneamino]pyridine-4-carboxamide
Also Known As: (E)-N'-((5-(4-((difluoromethyl)thio)phenyl)furan-2-yl)methylene)isonicotinohydrazide, N-((1E)-2-{5-[4-(difluoromethylthio)phenyl](2-furyl)}-1-azavinyl)-4-pyridylcar boxamide, N'-[(E)-(5-{4-[(difluoromethyl)sulfanyl]phenyl}furan-2-yl)methylidene]pyridine-4-carbohydrazide, N-[(E)-[5-[4-(difluoromethylsulfanyl)phenyl]furan-2-yl]methylideneamino]pyridine-4-carboxamide
| Molecular Formula | C18H13F2N3O2S |
|---|---|
| Molecular Weight | 373.07 g/mol |
| LogP | 4.4202 |
| Topological Polar Surface Area | 67.49 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 6 |
| Exact Mass | 373.06964 |
| Heavy Atoms | 26 |
| Complexity | 896.3144 |
Chemical Identifiers
| CAS Number | 488793-69-7 |
|---|---|
| SMILES | C1=CC(=CC=C1C2=CC=C(O2)/C=N/NC(=O)C3=CC=NC=C3)SC(F)F |
Product Overview
(E)-N'-((5-(4-((difluoromethyl)thio)phenyl)furan-2-yl)methylene)isonicotinohydrazide (CAS 488793-69-7), with molecular formula C18H13F2N3O2S and molecular weight 373.07 g/mol. IUPAC: N-[(E)-[5-[4-(difluoromethylsulfanyl)phenyl]furan-2-yl]methylideneamino]pyridine-4-carboxamide.
Chemical Property Profile of (E)-N'-((5-(4-((difluoromethyl)thio)phenyl)furan-2-yl)methylene)isonicotinohydrazide
Property Insights of (E)-N'-((5-(4-((difluoromethyl)thio)phenyl)furan-2-yl)methylene)isonicotinohydrazide
The XLogP value of 4.4202 indicates that (E)-N'-((5-(4-((difluoromethyl)thio)phenyl)furan-2-yl)methylene)isonicotinohydrazide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 67.49 Ų falls within the moderate polarity range, balancing permeability and solubility for (E)-N'-((5-(4-((difluoromethyl)thio)phenyl)furan-2-yl)methylene)isonicotinohydrazide. Following Lipinski's Rule of Five, (E)-N'-((5-(4-((difluoromethyl)thio)phenyl)furan-2-yl)methylene)isonicotinohydrazide has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-N'-((5-(4-((difluoromethyl)thio)phenyl)furan-2-yl)methylene)isonicotinohydrazide?
The CAS number of (E)-N'-((5-(4-((difluoromethyl)thio)phenyl)furan-2-yl)methylene)isonicotinohydrazide is 488793-69-7.
What is the molecular formula of (E)-N'-((5-(4-((difluoromethyl)thio)phenyl)furan-2-yl)methylene)isonicotinohydrazide?
The molecular formula of (E)-N'-((5-(4-((difluoromethyl)thio)phenyl)furan-2-yl)methylene)isonicotinohydrazide is C18H13F2N3O2S.
What is the molecular weight of (E)-N'-((5-(4-((difluoromethyl)thio)phenyl)furan-2-yl)methylene)isonicotinohydrazide?
The molecular weight of (E)-N'-((5-(4-((difluoromethyl)thio)phenyl)furan-2-yl)methylene)isonicotinohydrazide is 373.07 g/mol.
Where can I buy (E)-N'-((5-(4-((difluoromethyl)thio)phenyl)furan-2-yl)methylene)isonicotinohydrazide?
You can request a quote for (E)-N'-((5-(4-((difluoromethyl)thio)phenyl)furan-2-yl)methylene)isonicotinohydrazide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-N'-((5-(4-((difluoromethyl)thio)phenyl)furan-2-yl)methylene)isonicotinohydrazide?
Yes, KEHONG BIO provides custom synthesis services for (E)-N'-((5-(4-((difluoromethyl)thio)phenyl)furan-2-yl)methylene)isonicotinohydrazide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.