(E)-2-(4-(4-chlorobenzyl)piperazin-1-yl)-N'-(4-(methylthio)benzylidene)acetohydrazide
TL;DR: (E)-2-(4-(4-chlorobenzyl)piperazin-1-yl)-N'-(4-(methylthio)benzylidene)acetohydrazide (CAS 488716-35-4) is a chemical compound with molecular formula C21H25ClN4OS and molecular weight 416.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[4-[(4-chlorophenyl)methyl]piperazin-1-yl]-N-[(E)-(4-methylsulfanylphenyl)methylideneamino]acetamide
Also Known As: (E)-2-(4-(4-chlorobenzyl)piperazin-1-yl)-N'-(4-(methylthio)benzylidene)acetohydrazide, [4-(4-Chloro-benzyl)-piperazin-1-yl]-acetic acid [1-(4-methylsulfanyl-phenyl)-meth-(E)-ylidene]-hydrazide, 2-[4-(4-chlorobenzyl)piperazin-1-yl]-N'-{(E)-[4-(methylsulfanyl)phenyl]methylidene}acetohydrazide, 2-[4-[(4-chlorophenyl)methyl]piperazin-1-yl]-N-[(E)-(4-methylsulfanylphenyl)methylideneamino]acetamide, N-[(1E)-2-(4-methylthiophenyl)-1-azavinyl]-2-{4-[(4-chlorophenyl)methyl]pipera zinyl}acetamide
| Molecular Formula | C21H25ClN4OS |
|---|---|
| Molecular Weight | 416.14 g/mol |
| LogP | 3.3298 |
| Topological Polar Surface Area | 47.94 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 7 |
| Exact Mass | 416.14377 |
| Heavy Atoms | 28 |
| Complexity | 787.0578 |
Chemical Identifiers
| CAS Number | 488716-35-4 |
|---|---|
| SMILES | CSC1=CC=C(C=C1)/C=N/NC(=O)CN2CCN(CC2)CC3=CC=C(C=C3)Cl |
Product Overview
(E)-2-(4-(4-chlorobenzyl)piperazin-1-yl)-N'-(4-(methylthio)benzylidene)acetohydrazide (CAS 488716-35-4), with molecular formula C21H25ClN4OS and molecular weight 416.14 g/mol. IUPAC: 2-[4-[(4-chlorophenyl)methyl]piperazin-1-yl]-N-[(E)-(4-methylsulfanylphenyl)methylideneamino]acetamide.
Chemical Property Profile of (E)-2-(4-(4-chlorobenzyl)piperazin-1-yl)-N'-(4-(methylthio)benzylidene)acetohydrazide
Property Insights of (E)-2-(4-(4-chlorobenzyl)piperazin-1-yl)-N'-(4-(methylthio)benzylidene)acetohydrazide
The XLogP value of 3.3298 indicates that (E)-2-(4-(4-chlorobenzyl)piperazin-1-yl)-N'-(4-(methylthio)benzylidene)acetohydrazide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 47.94 Ų, (E)-2-(4-(4-chlorobenzyl)piperazin-1-yl)-N'-(4-(methylthio)benzylidene)acetohydrazide exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (E)-2-(4-(4-chlorobenzyl)piperazin-1-yl)-N'-(4-(methylthio)benzylidene)acetohydrazide has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-2-(4-(4-chlorobenzyl)piperazin-1-yl)-N'-(4-(methylthio)benzylidene)acetohydrazide?
The CAS number of (E)-2-(4-(4-chlorobenzyl)piperazin-1-yl)-N'-(4-(methylthio)benzylidene)acetohydrazide is 488716-35-4.
What is the molecular formula of (E)-2-(4-(4-chlorobenzyl)piperazin-1-yl)-N'-(4-(methylthio)benzylidene)acetohydrazide?
The molecular formula of (E)-2-(4-(4-chlorobenzyl)piperazin-1-yl)-N'-(4-(methylthio)benzylidene)acetohydrazide is C21H25ClN4OS.
What is the molecular weight of (E)-2-(4-(4-chlorobenzyl)piperazin-1-yl)-N'-(4-(methylthio)benzylidene)acetohydrazide?
The molecular weight of (E)-2-(4-(4-chlorobenzyl)piperazin-1-yl)-N'-(4-(methylthio)benzylidene)acetohydrazide is 416.14 g/mol.
Where can I buy (E)-2-(4-(4-chlorobenzyl)piperazin-1-yl)-N'-(4-(methylthio)benzylidene)acetohydrazide?
You can request a quote for (E)-2-(4-(4-chlorobenzyl)piperazin-1-yl)-N'-(4-(methylthio)benzylidene)acetohydrazide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-2-(4-(4-chlorobenzyl)piperazin-1-yl)-N'-(4-(methylthio)benzylidene)acetohydrazide?
Yes, KEHONG BIO provides custom synthesis services for (E)-2-(4-(4-chlorobenzyl)piperazin-1-yl)-N'-(4-(methylthio)benzylidene)acetohydrazide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.