(Z)-2-(4-benzylpiperidin-1-yl)-5-(2,4,5-trimethoxybenzylidene)thiazol-4(5H)-one
TL;DR: (Z)-2-(4-benzylpiperidin-1-yl)-5-(2,4,5-trimethoxybenzylidene)thiazol-4(5H)-one (CAS 488705-78-8) is a chemical compound with molecular formula C25H28N2O4S and molecular weight 452.18 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5Z)-2-(4-benzylpiperidin-1-yl)-5-[(2,4,5-trimethoxyphenyl)methylidene]-1,3-thiazol-4-one
Also Known As: (Z)-2-(4-benzylpiperidin-1-yl)-5-(2,4,5-trimethoxybenzylidene)thiazol-4(5H)-one, (5Z)-2-(4-benzylpiperidin-1-yl)-5-(2,4,5-trimethoxybenzylidene)-1,3-thiazol-4(5H)-one, 2-(4-benzyl-1-piperidyl)-5-[(2,4,5-trimethoxyphenyl)methylidene]-1,3-thiazol-4-one, (5Z)-2-(4-benzylpiperidin-1-yl)-5-[(2,4,5-trimethoxyphenyl)methylidene]-1,3-thiazol-4-one
| Molecular Formula | C25H28N2O4S |
|---|---|
| Molecular Weight | 452.18 g/mol |
| LogP | 4.6374 |
| Topological Polar Surface Area | 60.36 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 6 |
| Exact Mass | 452.17697 |
| Heavy Atoms | 32 |
| Complexity | 1027.7374 |
Chemical Identifiers
| CAS Number | 488705-78-8 |
|---|---|
| SMILES | COC1=CC(=C(C=C1/C=C\2/C(=O)N=C(S2)N3CCC(CC3)CC4=CC=CC=C4)OC)OC |
Product Overview
(Z)-2-(4-benzylpiperidin-1-yl)-5-(2,4,5-trimethoxybenzylidene)thiazol-4(5H)-one (CAS 488705-78-8), with molecular formula C25H28N2O4S and molecular weight 452.18 g/mol. IUPAC: (5Z)-2-(4-benzylpiperidin-1-yl)-5-[(2,4,5-trimethoxyphenyl)methylidene]-1,3-thiazol-4-one.
Chemical Property Profile of (Z)-2-(4-benzylpiperidin-1-yl)-5-(2,4,5-trimethoxybenzylidene)thiazol-4(5H)-one
Property Insights of (Z)-2-(4-benzylpiperidin-1-yl)-5-(2,4,5-trimethoxybenzylidene)thiazol-4(5H)-one
The XLogP value of 4.6374 indicates that (Z)-2-(4-benzylpiperidin-1-yl)-5-(2,4,5-trimethoxybenzylidene)thiazol-4(5H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 60.36 Ų falls within the moderate polarity range, balancing permeability and solubility for (Z)-2-(4-benzylpiperidin-1-yl)-5-(2,4,5-trimethoxybenzylidene)thiazol-4(5H)-one. Following Lipinski's Rule of Five, (Z)-2-(4-benzylpiperidin-1-yl)-5-(2,4,5-trimethoxybenzylidene)thiazol-4(5H)-one has 0 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (Z)-2-(4-benzylpiperidin-1-yl)-5-(2,4,5-trimethoxybenzylidene)thiazol-4(5H)-one?
The CAS number of (Z)-2-(4-benzylpiperidin-1-yl)-5-(2,4,5-trimethoxybenzylidene)thiazol-4(5H)-one is 488705-78-8.
What is the molecular formula of (Z)-2-(4-benzylpiperidin-1-yl)-5-(2,4,5-trimethoxybenzylidene)thiazol-4(5H)-one?
The molecular formula of (Z)-2-(4-benzylpiperidin-1-yl)-5-(2,4,5-trimethoxybenzylidene)thiazol-4(5H)-one is C25H28N2O4S.
What is the molecular weight of (Z)-2-(4-benzylpiperidin-1-yl)-5-(2,4,5-trimethoxybenzylidene)thiazol-4(5H)-one?
The molecular weight of (Z)-2-(4-benzylpiperidin-1-yl)-5-(2,4,5-trimethoxybenzylidene)thiazol-4(5H)-one is 452.18 g/mol.
Where can I buy (Z)-2-(4-benzylpiperidin-1-yl)-5-(2,4,5-trimethoxybenzylidene)thiazol-4(5H)-one?
You can request a quote for (Z)-2-(4-benzylpiperidin-1-yl)-5-(2,4,5-trimethoxybenzylidene)thiazol-4(5H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (Z)-2-(4-benzylpiperidin-1-yl)-5-(2,4,5-trimethoxybenzylidene)thiazol-4(5H)-one?
Yes, KEHONG BIO provides custom synthesis services for (Z)-2-(4-benzylpiperidin-1-yl)-5-(2,4,5-trimethoxybenzylidene)thiazol-4(5H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.