6-Bromo-4-(2-chloro-phenyl)-2-piperazin-1-yl-quinazoline
TL;DR: 6-Bromo-4-(2-chloro-phenyl)-2-piperazin-1-yl-quinazoline (CAS 488704-92-3) is a chemical compound with molecular formula C18H16BrClN4 and molecular weight 402.02 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6-bromo-4-(2-chlorophenyl)-2-piperazin-1-ylquinazoline
Also Known As: 6-Bromo-4-(2-chloro-phenyl)-2-piperazin-1-yl-quinazoline, 6-bromo-4-(2-chlorophenyl)-2-(piperazin-1-yl)quinazoline, 6-bromo-4-(2-chlorophenyl)-2-piperazin-1-ylquinazoline
| Molecular Formula | C18H16BrClN4 |
|---|---|
| Molecular Weight | 402.02 g/mol |
| LogP | 4.1223 |
| Topological Polar Surface Area | 41.05 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 402.0247 |
| Heavy Atoms | 24 |
| Complexity | 893.3212 |
Chemical Identifiers
| CAS Number | 488704-92-3 |
|---|---|
| SMILES | C1CN(CCN1)C2=NC3=C(C=C(C=C3)Br)C(=N2)C4=CC=CC=C4Cl |
Product Overview
6-Bromo-4-(2-chloro-phenyl)-2-piperazin-1-yl-quinazoline (CAS 488704-92-3), with molecular formula C18H16BrClN4 and molecular weight 402.02 g/mol. IUPAC: 6-bromo-4-(2-chlorophenyl)-2-piperazin-1-ylquinazoline.
Chemical Property Profile of 6-Bromo-4-(2-chloro-phenyl)-2-piperazin-1-yl-quinazoline
Property Insights of 6-Bromo-4-(2-chloro-phenyl)-2-piperazin-1-yl-quinazoline
The XLogP value of 4.1223 indicates that 6-Bromo-4-(2-chloro-phenyl)-2-piperazin-1-yl-quinazoline is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 41.05 Ų, 6-Bromo-4-(2-chloro-phenyl)-2-piperazin-1-yl-quinazoline exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 6-Bromo-4-(2-chloro-phenyl)-2-piperazin-1-yl-quinazoline has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 6-Bromo-4-(2-chloro-phenyl)-2-piperazin-1-yl-quinazoline?
The CAS number of 6-Bromo-4-(2-chloro-phenyl)-2-piperazin-1-yl-quinazoline is 488704-92-3.
What is the molecular formula of 6-Bromo-4-(2-chloro-phenyl)-2-piperazin-1-yl-quinazoline?
The molecular formula of 6-Bromo-4-(2-chloro-phenyl)-2-piperazin-1-yl-quinazoline is C18H16BrClN4.
What is the molecular weight of 6-Bromo-4-(2-chloro-phenyl)-2-piperazin-1-yl-quinazoline?
The molecular weight of 6-Bromo-4-(2-chloro-phenyl)-2-piperazin-1-yl-quinazoline is 402.02 g/mol.
Where can I buy 6-Bromo-4-(2-chloro-phenyl)-2-piperazin-1-yl-quinazoline?
You can request a quote for 6-Bromo-4-(2-chloro-phenyl)-2-piperazin-1-yl-quinazoline directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 6-Bromo-4-(2-chloro-phenyl)-2-piperazin-1-yl-quinazoline?
Yes, KEHONG BIO provides custom synthesis services for 6-Bromo-4-(2-chloro-phenyl)-2-piperazin-1-yl-quinazoline and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.