![(4E)-4-[hydroxy(thiophen-2-yl)methylidene]-5-(4-nitrophenyl)-1-(tetrahydrofuran-2-ylmethyl)pyrrolidine-2,3-dione structure](/static/products/488/488136-53-4.png)
(4E)-4-[hydroxy(thiophen-2-yl)methylidene]-5-(4-nitrophenyl)-1-(tetrahydrofuran-2-ylmethyl)pyrrolidine-2,3-dione
TL;DR: (4E)-4-[hydroxy(thiophen-2-yl)methylidene]-5-(4-nitrophenyl)-1-(tetrahydrofuran-2-ylmethyl)pyrrolidine-2,3-dione (CAS 488136-53-4) is a chemical compound with molecular formula C20H18N2O6S and molecular weight 414.09 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-hydroxy-2-(4-nitrophenyl)-1-(oxolan-2-ylmethyl)-3-(thiophene-2-carbonyl)-2H-pyrrol-5-one
Also Known As: (4E)-4-[hydroxy(thiophen-2-yl)methylidene]-5-(4-nitrophenyl)-1-(tetrahydrofuran-2-ylmethyl)pyrrolidine-2,3-dione, 3-hydroxy-5-(4-nitrophenyl)-1-((tetrahydrofuran-2-yl)methyl)-4-(thiophene-2-carbonyl)-1H-pyrrol-2(5H)-one, 4-hydroxy-2-(4-nitrophenyl)-1-(oxolan-2-ylmethyl)-3-(thiophene-2-carbonyl)-2H-pyrrol-5-one
| Molecular Formula | C20H18N2O6S |
|---|---|
| Molecular Weight | 414.09 g/mol |
| LogP | 3.4136 |
| Topological Polar Surface Area | 109.98 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 6 |
| Exact Mass | 414.08856 |
| Heavy Atoms | 29 |
| Complexity | 976.91016 |
Chemical Identifiers
| CAS Number | 488136-53-4 |
|---|---|
| SMILES | C1CC(OC1)CN2C(C(=C(C2=O)O)C(=O)C3=CC=CS3)C4=CC=C(C=C4)[N+](=O)[O-] |
Product Overview
(4E)-4-[hydroxy(thiophen-2-yl)methylidene]-5-(4-nitrophenyl)-1-(tetrahydrofuran-2-ylmethyl)pyrrolidine-2,3-dione (CAS 488136-53-4), with molecular formula C20H18N2O6S and molecular weight 414.09 g/mol. IUPAC: 4-hydroxy-2-(4-nitrophenyl)-1-(oxolan-2-ylmethyl)-3-(thiophene-2-carbonyl)-2H-pyrrol-5-one.
Chemical Property Profile of (4E)-4-[hydroxy(thiophen-2-yl)methylidene]-5-(4-nitrophenyl)-1-(tetrahydrofuran-2-ylmethyl)pyrrolidine-2,3-dione
Property Insights of (4E)-4-[hydroxy(thiophen-2-yl)methylidene]-5-(4-nitrophenyl)-1-(tetrahydrofuran-2-ylmethyl)pyrrolidine-2,3-dione
The XLogP value of 3.4136 indicates that (4E)-4-[hydroxy(thiophen-2-yl)methylidene]-5-(4-nitrophenyl)-1-(tetrahydrofuran-2-ylmethyl)pyrrolidine-2,3-dione is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 109.98 Ų falls within the moderate polarity range, balancing permeability and solubility for (4E)-4-[hydroxy(thiophen-2-yl)methylidene]-5-(4-nitrophenyl)-1-(tetrahydrofuran-2-ylmethyl)pyrrolidine-2,3-dione. Following Lipinski's Rule of Five, (4E)-4-[hydroxy(thiophen-2-yl)methylidene]-5-(4-nitrophenyl)-1-(tetrahydrofuran-2-ylmethyl)pyrrolidine-2,3-dione has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (4E)-4-[hydroxy(thiophen-2-yl)methylidene]-5-(4-nitrophenyl)-1-(tetrahydrofuran-2-ylmethyl)pyrrolidine-2,3-dione?
The CAS number of (4E)-4-[hydroxy(thiophen-2-yl)methylidene]-5-(4-nitrophenyl)-1-(tetrahydrofuran-2-ylmethyl)pyrrolidine-2,3-dione is 488136-53-4.
What is the molecular formula of (4E)-4-[hydroxy(thiophen-2-yl)methylidene]-5-(4-nitrophenyl)-1-(tetrahydrofuran-2-ylmethyl)pyrrolidine-2,3-dione?
The molecular formula of (4E)-4-[hydroxy(thiophen-2-yl)methylidene]-5-(4-nitrophenyl)-1-(tetrahydrofuran-2-ylmethyl)pyrrolidine-2,3-dione is C20H18N2O6S.
What is the molecular weight of (4E)-4-[hydroxy(thiophen-2-yl)methylidene]-5-(4-nitrophenyl)-1-(tetrahydrofuran-2-ylmethyl)pyrrolidine-2,3-dione?
The molecular weight of (4E)-4-[hydroxy(thiophen-2-yl)methylidene]-5-(4-nitrophenyl)-1-(tetrahydrofuran-2-ylmethyl)pyrrolidine-2,3-dione is 414.09 g/mol.
Where can I buy (4E)-4-[hydroxy(thiophen-2-yl)methylidene]-5-(4-nitrophenyl)-1-(tetrahydrofuran-2-ylmethyl)pyrrolidine-2,3-dione?
You can request a quote for (4E)-4-[hydroxy(thiophen-2-yl)methylidene]-5-(4-nitrophenyl)-1-(tetrahydrofuran-2-ylmethyl)pyrrolidine-2,3-dione directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (4E)-4-[hydroxy(thiophen-2-yl)methylidene]-5-(4-nitrophenyl)-1-(tetrahydrofuran-2-ylmethyl)pyrrolidine-2,3-dione?
Yes, KEHONG BIO provides custom synthesis services for (4E)-4-[hydroxy(thiophen-2-yl)methylidene]-5-(4-nitrophenyl)-1-(tetrahydrofuran-2-ylmethyl)pyrrolidine-2,3-dione and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.