(E)-N'-(3-hydroxybenzylidene)-2-((5-((naphthalen-1-ylmethyl)thio)-1,3,4-thiadiazol-2-yl)thio)acetohydrazide
TL;DR: (E)-N'-(3-hydroxybenzylidene)-2-((5-((naphthalen-1-ylmethyl)thio)-1,3,4-thiadiazol-2-yl)thio)acetohydrazide (CAS 488133-07-9) is a chemical compound with molecular formula C22H18N4O2S3 and molecular weight 466.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[(E)-(3-hydroxyphenyl)methylideneamino]-2-[[5-(naphthalen-1-ylmethylsulfanyl)-1,3,4-thiadiazol-2-yl]sulfanyl]acetamide
Also Known As: (E)-N'-(3-hydroxybenzylidene)-2-((5-((naphthalen-1-ylmethyl)thio)-1,3,4-thiadiazol-2-yl)thio)acetohydrazide, N'-[(E)-(3-hydroxyphenyl)methylidene]-2-({5-[(naphthalen-1-ylmethyl)sulfanyl]-1,3,4-thiadiazol-2-yl}sulfanyl)acetohydrazide, N-[(1E)-2-(3-hydroxyphenyl)-1-azavinyl]-2-[5-(naphthylmethylthio)(1,3,4-thiadi azol-2-ylthio)]acetamide, N-[(E)-(3-hydroxyphenyl)methylideneamino]-2-[[5-(naphthalen-1-ylmethylsulfanyl)-1,3,4-thiadiazol-2-yl]sulfanyl]acetamide
| Molecular Formula | C22H18N4O2S3 |
|---|---|
| Molecular Weight | 466.06 g/mol |
| LogP | 4.9316 |
| Topological Polar Surface Area | 87.47 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 8 |
| Exact Mass | 466.0592 |
| Heavy Atoms | 31 |
| Complexity | 1220.8479 |
Chemical Identifiers
| CAS Number | 488133-07-9 |
|---|---|
| SMILES | C1=CC=C2C(=C1)C=CC=C2CSC3=NN=C(S3)SCC(=O)N/N=C/C4=CC(=CC=C4)O |
Product Overview
(E)-N'-(3-hydroxybenzylidene)-2-((5-((naphthalen-1-ylmethyl)thio)-1,3,4-thiadiazol-2-yl)thio)acetohydrazide (CAS 488133-07-9), with molecular formula C22H18N4O2S3 and molecular weight 466.06 g/mol. IUPAC: N-[(E)-(3-hydroxyphenyl)methylideneamino]-2-[[5-(naphthalen-1-ylmethylsulfanyl)-1,3,4-thiadiazol-2-yl]sulfanyl]acetamide.
Chemical Property Profile of (E)-N'-(3-hydroxybenzylidene)-2-((5-((naphthalen-1-ylmethyl)thio)-1,3,4-thiadiazol-2-yl)thio)acetohydrazide
Property Insights of (E)-N'-(3-hydroxybenzylidene)-2-((5-((naphthalen-1-ylmethyl)thio)-1,3,4-thiadiazol-2-yl)thio)acetohydrazide
The XLogP value of 4.9316 indicates that (E)-N'-(3-hydroxybenzylidene)-2-((5-((naphthalen-1-ylmethyl)thio)-1,3,4-thiadiazol-2-yl)thio)acetohydrazide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 87.47 Ų falls within the moderate polarity range, balancing permeability and solubility for (E)-N'-(3-hydroxybenzylidene)-2-((5-((naphthalen-1-ylmethyl)thio)-1,3,4-thiadiazol-2-yl)thio)acetohydrazide. Following Lipinski's Rule of Five, (E)-N'-(3-hydroxybenzylidene)-2-((5-((naphthalen-1-ylmethyl)thio)-1,3,4-thiadiazol-2-yl)thio)acetohydrazide has 2 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-N'-(3-hydroxybenzylidene)-2-((5-((naphthalen-1-ylmethyl)thio)-1,3,4-thiadiazol-2-yl)thio)acetohydrazide?
The CAS number of (E)-N'-(3-hydroxybenzylidene)-2-((5-((naphthalen-1-ylmethyl)thio)-1,3,4-thiadiazol-2-yl)thio)acetohydrazide is 488133-07-9.
What is the molecular formula of (E)-N'-(3-hydroxybenzylidene)-2-((5-((naphthalen-1-ylmethyl)thio)-1,3,4-thiadiazol-2-yl)thio)acetohydrazide?
The molecular formula of (E)-N'-(3-hydroxybenzylidene)-2-((5-((naphthalen-1-ylmethyl)thio)-1,3,4-thiadiazol-2-yl)thio)acetohydrazide is C22H18N4O2S3.
What is the molecular weight of (E)-N'-(3-hydroxybenzylidene)-2-((5-((naphthalen-1-ylmethyl)thio)-1,3,4-thiadiazol-2-yl)thio)acetohydrazide?
The molecular weight of (E)-N'-(3-hydroxybenzylidene)-2-((5-((naphthalen-1-ylmethyl)thio)-1,3,4-thiadiazol-2-yl)thio)acetohydrazide is 466.06 g/mol.
Where can I buy (E)-N'-(3-hydroxybenzylidene)-2-((5-((naphthalen-1-ylmethyl)thio)-1,3,4-thiadiazol-2-yl)thio)acetohydrazide?
You can request a quote for (E)-N'-(3-hydroxybenzylidene)-2-((5-((naphthalen-1-ylmethyl)thio)-1,3,4-thiadiazol-2-yl)thio)acetohydrazide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-N'-(3-hydroxybenzylidene)-2-((5-((naphthalen-1-ylmethyl)thio)-1,3,4-thiadiazol-2-yl)thio)acetohydrazide?
Yes, KEHONG BIO provides custom synthesis services for (E)-N'-(3-hydroxybenzylidene)-2-((5-((naphthalen-1-ylmethyl)thio)-1,3,4-thiadiazol-2-yl)thio)acetohydrazide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.