4-(3,4-dimethoxyphenyl)-6-(4-fluorophenyl)-3,4-dihydropyrimidine-2(1H)-thione
TL;DR: 4-(3,4-dimethoxyphenyl)-6-(4-fluorophenyl)-3,4-dihydropyrimidine-2(1H)-thione (CAS 488132-47-4) is a chemical compound with molecular formula C18H17FN2O2S and molecular weight 344.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
4-(3,4-dimethoxyphenyl)-6-(4-fluorophenyl)-3,4-dihydro-1H-pyrimidine-2-thione
Also Known As: ChemDiv3_004762, IDI1_022672, 4-(3,4-dimethoxyphenyl)-6-(4-fluorophenyl)-3,4-dihydropyrimidine-2(1H)-thione, 4-(3,4-dimethoxyphenyl)-6-(4-fluorophenyl)-3,4-dihydro-1H-pyrimidine-2-thione, 4-(3,4-DIMETHOXYPHENYL)-6-(4-FLUOROPHENYL)-1,2,3,4-TETRAHYDROPYRIMIDINE-2-THIONE
| Molecular Formula | C18H17FN2O2S |
|---|---|
| Molecular Weight | 344.10 g/mol |
| LogP | 3.4028 |
| Topological Polar Surface Area | 42.52 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 4 |
| Exact Mass | 344.0995 |
| Heavy Atoms | 24 |
| Complexity | 790.10583 |
Chemical Identifiers
| CAS Number | 488132-47-4 |
|---|---|
| SMILES | COC1=C(C=C(C=C1)C2C=C(NC(=S)N2)C3=CC=C(C=C3)F)OC |
Product Overview
4-(3,4-dimethoxyphenyl)-6-(4-fluorophenyl)-3,4-dihydropyrimidine-2(1H)-thione (CAS 488132-47-4), with molecular formula C18H17FN2O2S and molecular weight 344.10 g/mol. IUPAC: 4-(3,4-dimethoxyphenyl)-6-(4-fluorophenyl)-3,4-dihydro-1H-pyrimidine-2-thione.
Chemical Property Profile of 4-(3,4-dimethoxyphenyl)-6-(4-fluorophenyl)-3,4-dihydropyrimidine-2(1H)-thione
Property Insights of 4-(3,4-dimethoxyphenyl)-6-(4-fluorophenyl)-3,4-dihydropyrimidine-2(1H)-thione
The XLogP value of 3.4028 indicates that 4-(3,4-dimethoxyphenyl)-6-(4-fluorophenyl)-3,4-dihydropyrimidine-2(1H)-thione is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 42.52 Ų, 4-(3,4-dimethoxyphenyl)-6-(4-fluorophenyl)-3,4-dihydropyrimidine-2(1H)-thione exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 4-(3,4-dimethoxyphenyl)-6-(4-fluorophenyl)-3,4-dihydropyrimidine-2(1H)-thione has 2 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 4-(3,4-dimethoxyphenyl)-6-(4-fluorophenyl)-3,4-dihydropyrimidine-2(1H)-thione?
The CAS number of 4-(3,4-dimethoxyphenyl)-6-(4-fluorophenyl)-3,4-dihydropyrimidine-2(1H)-thione is 488132-47-4.
What is the molecular formula of 4-(3,4-dimethoxyphenyl)-6-(4-fluorophenyl)-3,4-dihydropyrimidine-2(1H)-thione?
The molecular formula of 4-(3,4-dimethoxyphenyl)-6-(4-fluorophenyl)-3,4-dihydropyrimidine-2(1H)-thione is C18H17FN2O2S.
What is the molecular weight of 4-(3,4-dimethoxyphenyl)-6-(4-fluorophenyl)-3,4-dihydropyrimidine-2(1H)-thione?
The molecular weight of 4-(3,4-dimethoxyphenyl)-6-(4-fluorophenyl)-3,4-dihydropyrimidine-2(1H)-thione is 344.10 g/mol.
Where can I buy 4-(3,4-dimethoxyphenyl)-6-(4-fluorophenyl)-3,4-dihydropyrimidine-2(1H)-thione?
You can request a quote for 4-(3,4-dimethoxyphenyl)-6-(4-fluorophenyl)-3,4-dihydropyrimidine-2(1H)-thione directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 4-(3,4-dimethoxyphenyl)-6-(4-fluorophenyl)-3,4-dihydropyrimidine-2(1H)-thione?
Yes, KEHONG BIO provides custom synthesis services for 4-(3,4-dimethoxyphenyl)-6-(4-fluorophenyl)-3,4-dihydropyrimidine-2(1H)-thione and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.