![1-[3-amino-5-hydroxy-4-(3,4,5-trimethoxyphenyl)-4,6,7,8-tetrahydrothieno[2,3-b]quinolin-2-yl]ethanone structure](/static/products/488/488130-71-8.png)
1-[3-amino-5-hydroxy-4-(3,4,5-trimethoxyphenyl)-4,6,7,8-tetrahydrothieno[2,3-b]quinolin-2-yl]ethanone
TL;DR: 1-[3-amino-5-hydroxy-4-(3,4,5-trimethoxyphenyl)-4,6,7,8-tetrahydrothieno[2,3-b]quinolin-2-yl]ethanone (CAS 488130-71-8) is a chemical compound with molecular formula C22H24N2O5S and molecular weight 428.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-acetyl-3-amino-4-(3,4,5-trimethoxyphenyl)-6,7,8,9-tetrahydro-4H-thieno[2,3-b]quinolin-5-one
Also Known As: 1-[3-amino-5-hydroxy-4-(3,4,5-trimethoxyphenyl)-4,6,7,8-tetrahydrothieno[2,3-b]quinolin-2-yl]ethanone, 2-acetyl-3-amino-4-(3,4,5-trimethoxyphenyl)-6,7,8,9-tetrahydro-4H-thieno[2,3-b]quinolin-5-one, 2-acetyl-3-amino-4-(3,4,5-trimethoxyphenyl)-6,7,8,9-tetrahydrothieno[2,3-b]quinolin-5(4H)-one
| Molecular Formula | C22H24N2O5S |
|---|---|
| Molecular Weight | 428.14 g/mol |
| LogP | 4.1232 |
| Topological Polar Surface Area | 99.88 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 8 |
| Rotatable Bonds | 5 |
| Exact Mass | 428.1406 |
| Heavy Atoms | 30 |
| Complexity | 1060.4324 |
Chemical Identifiers
| CAS Number | 488130-71-8 |
|---|---|
| SMILES | CC(=O)C1=C(C2=C(S1)NC3=C(C2C4=CC(=C(C(=C4)OC)OC)OC)C(=O)CCC3)N |
Product Overview
1-[3-amino-5-hydroxy-4-(3,4,5-trimethoxyphenyl)-4,6,7,8-tetrahydrothieno[2,3-b]quinolin-2-yl]ethanone (CAS 488130-71-8), with molecular formula C22H24N2O5S and molecular weight 428.14 g/mol. IUPAC: 2-acetyl-3-amino-4-(3,4,5-trimethoxyphenyl)-6,7,8,9-tetrahydro-4H-thieno[2,3-b]quinolin-5-one.
Chemical Property Profile of 1-[3-amino-5-hydroxy-4-(3,4,5-trimethoxyphenyl)-4,6,7,8-tetrahydrothieno[2,3-b]quinolin-2-yl]ethanone
Property Insights of 1-[3-amino-5-hydroxy-4-(3,4,5-trimethoxyphenyl)-4,6,7,8-tetrahydrothieno[2,3-b]quinolin-2-yl]ethanone
The XLogP value of 4.1232 indicates that 1-[3-amino-5-hydroxy-4-(3,4,5-trimethoxyphenyl)-4,6,7,8-tetrahydrothieno[2,3-b]quinolin-2-yl]ethanone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 99.88 Ų falls within the moderate polarity range, balancing permeability and solubility for 1-[3-amino-5-hydroxy-4-(3,4,5-trimethoxyphenyl)-4,6,7,8-tetrahydrothieno[2,3-b]quinolin-2-yl]ethanone. Following Lipinski's Rule of Five, 1-[3-amino-5-hydroxy-4-(3,4,5-trimethoxyphenyl)-4,6,7,8-tetrahydrothieno[2,3-b]quinolin-2-yl]ethanone has 2 hydrogen bond donor(s) and 8 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 1-[3-amino-5-hydroxy-4-(3,4,5-trimethoxyphenyl)-4,6,7,8-tetrahydrothieno[2,3-b]quinolin-2-yl]ethanone?
The CAS number of 1-[3-amino-5-hydroxy-4-(3,4,5-trimethoxyphenyl)-4,6,7,8-tetrahydrothieno[2,3-b]quinolin-2-yl]ethanone is 488130-71-8.
What is the molecular formula of 1-[3-amino-5-hydroxy-4-(3,4,5-trimethoxyphenyl)-4,6,7,8-tetrahydrothieno[2,3-b]quinolin-2-yl]ethanone?
The molecular formula of 1-[3-amino-5-hydroxy-4-(3,4,5-trimethoxyphenyl)-4,6,7,8-tetrahydrothieno[2,3-b]quinolin-2-yl]ethanone is C22H24N2O5S.
What is the molecular weight of 1-[3-amino-5-hydroxy-4-(3,4,5-trimethoxyphenyl)-4,6,7,8-tetrahydrothieno[2,3-b]quinolin-2-yl]ethanone?
The molecular weight of 1-[3-amino-5-hydroxy-4-(3,4,5-trimethoxyphenyl)-4,6,7,8-tetrahydrothieno[2,3-b]quinolin-2-yl]ethanone is 428.14 g/mol.
Where can I buy 1-[3-amino-5-hydroxy-4-(3,4,5-trimethoxyphenyl)-4,6,7,8-tetrahydrothieno[2,3-b]quinolin-2-yl]ethanone?
You can request a quote for 1-[3-amino-5-hydroxy-4-(3,4,5-trimethoxyphenyl)-4,6,7,8-tetrahydrothieno[2,3-b]quinolin-2-yl]ethanone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 1-[3-amino-5-hydroxy-4-(3,4,5-trimethoxyphenyl)-4,6,7,8-tetrahydrothieno[2,3-b]quinolin-2-yl]ethanone?
Yes, KEHONG BIO provides custom synthesis services for 1-[3-amino-5-hydroxy-4-(3,4,5-trimethoxyphenyl)-4,6,7,8-tetrahydrothieno[2,3-b]quinolin-2-yl]ethanone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.