(E)-N'-((3-benzyl-4-chloro-2-oxo-2,3-dihydrothiazol-5-yl)methylene)benzohydrazide
TL;DR: (E)-N'-((3-benzyl-4-chloro-2-oxo-2,3-dihydrothiazol-5-yl)methylene)benzohydrazide (CAS 488100-72-7) is a chemical compound with molecular formula C18H14ClN3O2S and molecular weight 371.05 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[(E)-(3-benzyl-4-chloro-2-oxo-1,3-thiazol-5-yl)methylideneamino]benzamide
Also Known As: (E)-N'-((3-benzyl-4-chloro-2-oxo-2,3-dihydrothiazol-5-yl)methylene)benzohydrazide, N'-[(E)-(3-benzyl-4-chloro-2-oxo-2,3-dihydro-1,3-thiazol-5-yl)methylidene]benzohydrazide, N-[(E)-(3-benzyl-4-chloro-2-oxo-1,3-thiazol-5-yl)methylideneamino]benzamide, N-{(1E)-2-[4-chloro-2-oxo-3-benzyl(1,3-thiazolin-5-yl)]-1-azavinyl}benzamide
| Molecular Formula | C18H14ClN3O2S |
|---|---|
| Molecular Weight | 371.05 g/mol |
| LogP | 3.3754 |
| Topological Polar Surface Area | 63.46 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 5 |
| Exact Mass | 371.04953 |
| Heavy Atoms | 25 |
| Complexity | 949.45746 |
Chemical Identifiers
| CAS Number | 488100-72-7 |
|---|---|
| SMILES | C1=CC=C(C=C1)CN2C(=C(SC2=O)/C=N/NC(=O)C3=CC=CC=C3)Cl |
Product Overview
(E)-N'-((3-benzyl-4-chloro-2-oxo-2,3-dihydrothiazol-5-yl)methylene)benzohydrazide (CAS 488100-72-7), with molecular formula C18H14ClN3O2S and molecular weight 371.05 g/mol. IUPAC: N-[(E)-(3-benzyl-4-chloro-2-oxo-1,3-thiazol-5-yl)methylideneamino]benzamide.
Chemical Property Profile of (E)-N'-((3-benzyl-4-chloro-2-oxo-2,3-dihydrothiazol-5-yl)methylene)benzohydrazide
Property Insights of (E)-N'-((3-benzyl-4-chloro-2-oxo-2,3-dihydrothiazol-5-yl)methylene)benzohydrazide
The XLogP value of 3.3754 indicates that (E)-N'-((3-benzyl-4-chloro-2-oxo-2,3-dihydrothiazol-5-yl)methylene)benzohydrazide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 63.46 Ų falls within the moderate polarity range, balancing permeability and solubility for (E)-N'-((3-benzyl-4-chloro-2-oxo-2,3-dihydrothiazol-5-yl)methylene)benzohydrazide. Following Lipinski's Rule of Five, (E)-N'-((3-benzyl-4-chloro-2-oxo-2,3-dihydrothiazol-5-yl)methylene)benzohydrazide has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-N'-((3-benzyl-4-chloro-2-oxo-2,3-dihydrothiazol-5-yl)methylene)benzohydrazide?
The CAS number of (E)-N'-((3-benzyl-4-chloro-2-oxo-2,3-dihydrothiazol-5-yl)methylene)benzohydrazide is 488100-72-7.
What is the molecular formula of (E)-N'-((3-benzyl-4-chloro-2-oxo-2,3-dihydrothiazol-5-yl)methylene)benzohydrazide?
The molecular formula of (E)-N'-((3-benzyl-4-chloro-2-oxo-2,3-dihydrothiazol-5-yl)methylene)benzohydrazide is C18H14ClN3O2S.
What is the molecular weight of (E)-N'-((3-benzyl-4-chloro-2-oxo-2,3-dihydrothiazol-5-yl)methylene)benzohydrazide?
The molecular weight of (E)-N'-((3-benzyl-4-chloro-2-oxo-2,3-dihydrothiazol-5-yl)methylene)benzohydrazide is 371.05 g/mol.
Where can I buy (E)-N'-((3-benzyl-4-chloro-2-oxo-2,3-dihydrothiazol-5-yl)methylene)benzohydrazide?
You can request a quote for (E)-N'-((3-benzyl-4-chloro-2-oxo-2,3-dihydrothiazol-5-yl)methylene)benzohydrazide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-N'-((3-benzyl-4-chloro-2-oxo-2,3-dihydrothiazol-5-yl)methylene)benzohydrazide?
Yes, KEHONG BIO provides custom synthesis services for (E)-N'-((3-benzyl-4-chloro-2-oxo-2,3-dihydrothiazol-5-yl)methylene)benzohydrazide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.