(Z)-5-(2-chloro-6-fluorobenzylidene)-3-(2,4-dimethylphenyl)-2-thioxothiazolidin-4-one
TL;DR: (Z)-5-(2-chloro-6-fluorobenzylidene)-3-(2,4-dimethylphenyl)-2-thioxothiazolidin-4-one (CAS 488100-08-9) is a chemical compound with molecular formula C18H13ClFNOS2 and molecular weight 377.01 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(5Z)-5-[(2-chloro-6-fluorophenyl)methylidene]-3-(2,4-dimethylphenyl)-2-sulfanylidene-1,3-thiazolidin-4-one
Also Known As: (Z)-5-(2-chloro-6-fluorobenzylidene)-3-(2,4-dimethylphenyl)-2-thioxothiazolidin-4-one, (5Z)-5-(2-chloro-6-fluorobenzylidene)-3-(2,4-dimethylphenyl)-2-thioxo-1,3-thiazolidin-4-one, (5Z)-5-[(2-chloro-6-fluorophenyl)methylidene]-3-(2,4-dimethylphenyl)-2-sulfanylidene-1,3-thiazolidin-4-one, 3-(2,4-dimethylphenyl)-5-[(2-chloro-6-fluorophenyl)methylene]-2-thioxo-1,3-thi azolidin-4-one
| Molecular Formula | C18H13ClFNOS2 |
|---|---|
| Molecular Weight | 377.01 g/mol |
| LogP | 5.50174 |
| Topological Polar Surface Area | 20.31 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 3 |
| Rotatable Bonds | 2 |
| Exact Mass | 377.0111 |
| Heavy Atoms | 24 |
| Complexity | 874.33264 |
Chemical Identifiers
| CAS Number | 488100-08-9 |
|---|---|
| SMILES | CC1=CC(=C(C=C1)N2C(=O)/C(=C/C3=C(C=CC=C3Cl)F)/SC2=S)C |
Product Overview
(Z)-5-(2-chloro-6-fluorobenzylidene)-3-(2,4-dimethylphenyl)-2-thioxothiazolidin-4-one (CAS 488100-08-9), with molecular formula C18H13ClFNOS2 and molecular weight 377.01 g/mol. IUPAC: (5Z)-5-[(2-chloro-6-fluorophenyl)methylidene]-3-(2,4-dimethylphenyl)-2-sulfanylidene-1,3-thiazolidin-4-one.
Chemical Property Profile of (Z)-5-(2-chloro-6-fluorobenzylidene)-3-(2,4-dimethylphenyl)-2-thioxothiazolidin-4-one
Property Insights of (Z)-5-(2-chloro-6-fluorobenzylidene)-3-(2,4-dimethylphenyl)-2-thioxothiazolidin-4-one
The XLogP value of 5.50174 indicates that (Z)-5-(2-chloro-6-fluorobenzylidene)-3-(2,4-dimethylphenyl)-2-thioxothiazolidin-4-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 20.31 Ų, (Z)-5-(2-chloro-6-fluorobenzylidene)-3-(2,4-dimethylphenyl)-2-thioxothiazolidin-4-one exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, (Z)-5-(2-chloro-6-fluorobenzylidene)-3-(2,4-dimethylphenyl)-2-thioxothiazolidin-4-one has 0 hydrogen bond donor(s) and 3 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (Z)-5-(2-chloro-6-fluorobenzylidene)-3-(2,4-dimethylphenyl)-2-thioxothiazolidin-4-one?
The CAS number of (Z)-5-(2-chloro-6-fluorobenzylidene)-3-(2,4-dimethylphenyl)-2-thioxothiazolidin-4-one is 488100-08-9.
What is the molecular formula of (Z)-5-(2-chloro-6-fluorobenzylidene)-3-(2,4-dimethylphenyl)-2-thioxothiazolidin-4-one?
The molecular formula of (Z)-5-(2-chloro-6-fluorobenzylidene)-3-(2,4-dimethylphenyl)-2-thioxothiazolidin-4-one is C18H13ClFNOS2.
What is the molecular weight of (Z)-5-(2-chloro-6-fluorobenzylidene)-3-(2,4-dimethylphenyl)-2-thioxothiazolidin-4-one?
The molecular weight of (Z)-5-(2-chloro-6-fluorobenzylidene)-3-(2,4-dimethylphenyl)-2-thioxothiazolidin-4-one is 377.01 g/mol.
Where can I buy (Z)-5-(2-chloro-6-fluorobenzylidene)-3-(2,4-dimethylphenyl)-2-thioxothiazolidin-4-one?
You can request a quote for (Z)-5-(2-chloro-6-fluorobenzylidene)-3-(2,4-dimethylphenyl)-2-thioxothiazolidin-4-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (Z)-5-(2-chloro-6-fluorobenzylidene)-3-(2,4-dimethylphenyl)-2-thioxothiazolidin-4-one?
Yes, KEHONG BIO provides custom synthesis services for (Z)-5-(2-chloro-6-fluorobenzylidene)-3-(2,4-dimethylphenyl)-2-thioxothiazolidin-4-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.