![5-(4-Fluorophenyl)-1H-pyrazole-3-carboxylic acid 2-[1-(2-thienyl)ethylidene]hydrazide structure](/static/products/4880/488098-46-0.webp)
5-(4-Fluorophenyl)-1H-pyrazole-3-carboxylic acid 2-[1-(2-thienyl)ethylidene]hydrazide
TL;DR: 5-(4-Fluorophenyl)-1H-pyrazole-3-carboxylic acid 2-[1-(2-thienyl)ethylidene]hydrazide (CAS 488098-46-0) is a chemical compound with molecular formula C16H13FN4OS and molecular weight 328.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
3-(4-fluorophenyl)-N-(1-thiophen-2-ylethylideneamino)-1H-pyrazole-5-carboxamide
Also Known As: 5-(4-Fluorophenyl)-1H-pyrazole-3-carboxylic acid 2-[1-(2-thienyl)ethylidene]hydrazide, 3-(4-fluorophenyl)-N-(1-thiophen-2-ylethylideneamino)-1H-pyrazole-5-carboxamide, 5-(4-Fluorophenyl)-N'-[1-(thiophen-2-yl)ethylidene]-1H-pyrazole-3-carbohydrazide
| Molecular Formula | C16H13FN4OS |
|---|---|
| Molecular Weight | 328.08 g/mol |
| LogP | 3.5 |
| Topological Polar Surface Area | 98.4 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 328.0794 |
| Heavy Atoms | 23 |
| Complexity | 453.0 |
Chemical Identifiers
| CAS Number | 488098-46-0 |
|---|---|
| SMILES | CC(=NNC(=O)C1=CC(=NN1)C2=CC=C(C=C2)F)C3=CC=CS3 |
| InChIKey | PQJLCGZOCUPHQM-UHFFFAOYSA-N |
Product Overview
5-(4-Fluorophenyl)-1H-pyrazole-3-carboxylic acid 2-[1-(2-thienyl)ethylidene]hydrazide (CAS 488098-46-0), with molecular formula C16H13FN4OS and molecular weight 328.08 g/mol. IUPAC: 3-(4-fluorophenyl)-N-(1-thiophen-2-ylethylideneamino)-1H-pyrazole-5-carboxamide.
Chemical Property Profile of 5-(4-Fluorophenyl)-1H-pyrazole-3-carboxylic acid 2-[1-(2-thienyl)ethylidene]hydrazide
Property Insights of 5-(4-Fluorophenyl)-1H-pyrazole-3-carboxylic acid 2-[1-(2-thienyl)ethylidene]hydrazide
The XLogP value of 3.5 indicates that 5-(4-Fluorophenyl)-1H-pyrazole-3-carboxylic acid 2-[1-(2-thienyl)ethylidene]hydrazide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 98.4 Ų falls within the moderate polarity range, balancing permeability and solubility for 5-(4-Fluorophenyl)-1H-pyrazole-3-carboxylic acid 2-[1-(2-thienyl)ethylidene]hydrazide. Following Lipinski's Rule of Five, 5-(4-Fluorophenyl)-1H-pyrazole-3-carboxylic acid 2-[1-(2-thienyl)ethylidene]hydrazide has 2 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-(4-Fluorophenyl)-1H-pyrazole-3-carboxylic acid 2-[1-(2-thienyl)ethylidene]hydrazide?
The CAS number of 5-(4-Fluorophenyl)-1H-pyrazole-3-carboxylic acid 2-[1-(2-thienyl)ethylidene]hydrazide is 488098-46-0.
What is the molecular formula of 5-(4-Fluorophenyl)-1H-pyrazole-3-carboxylic acid 2-[1-(2-thienyl)ethylidene]hydrazide?
The molecular formula of 5-(4-Fluorophenyl)-1H-pyrazole-3-carboxylic acid 2-[1-(2-thienyl)ethylidene]hydrazide is C16H13FN4OS.
What is the molecular weight of 5-(4-Fluorophenyl)-1H-pyrazole-3-carboxylic acid 2-[1-(2-thienyl)ethylidene]hydrazide?
The molecular weight of 5-(4-Fluorophenyl)-1H-pyrazole-3-carboxylic acid 2-[1-(2-thienyl)ethylidene]hydrazide is 328.08 g/mol.
Where can I buy 5-(4-Fluorophenyl)-1H-pyrazole-3-carboxylic acid 2-[1-(2-thienyl)ethylidene]hydrazide?
You can request a quote for 5-(4-Fluorophenyl)-1H-pyrazole-3-carboxylic acid 2-[1-(2-thienyl)ethylidene]hydrazide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-(4-Fluorophenyl)-1H-pyrazole-3-carboxylic acid 2-[1-(2-thienyl)ethylidene]hydrazide?
Yes, KEHONG BIO provides custom synthesis services for 5-(4-Fluorophenyl)-1H-pyrazole-3-carboxylic acid 2-[1-(2-thienyl)ethylidene]hydrazide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.