3-hydroxy-1-(6-methylpyridin-2-yl)-4-(thiophene-2-carbonyl)-5-(p-tolyl)-1H-pyrrol-2(5H)-one structure

3-hydroxy-1-(6-methylpyridin-2-yl)-4-(thiophene-2-carbonyl)-5-(p-tolyl)-1H-pyrrol-2(5H)-one

TL;DR: 3-hydroxy-1-(6-methylpyridin-2-yl)-4-(thiophene-2-carbonyl)-5-(p-tolyl)-1H-pyrrol-2(5H)-one (CAS 487033-69-2) is a chemical compound with molecular formula C22H18N2O3S and molecular weight 390.10 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

4-hydroxy-2-(4-methylphenyl)-1-(6-methyl-2-pyridinyl)-3-(thiophene-2-carbonyl)-2H-pyrrol-5-one

Also Known As: 3-hydroxy-1-(6-methylpyridin-2-yl)-4-(thiophene-2-carbonyl)-5-(p-tolyl)-1H-pyrrol-2(5H)-one, 3-hydroxy-5-(4-methylphenyl)-1-(6-methylpyridin-2-yl)-4-(thiophene-2-carbonyl)-2,5-dihydro-1H-pyrrol-2-one, 4-hydroxy-2-(4-methylphenyl)-1-(6-methylpyridin-2-yl)-3-(thiophene-2-carbonyl)-2H-pyrrol-5-one, (E)-[2-(4-methylphenyl)-1-(6-methylpyridinium-2-yl)-4,5-dioxopyrrolidin-3-ylidene](thiophen-2-yl)methanolate, 3-hydroxy-1-(6-methyl(2-pyridyl))-5-(4-methylphenyl)-4-(2-thienylcarbonyl)-3-p yrrolin-2-one

CAS: 487033-69-2
Molecular Formula C22H18N2O3S
Molecular Weight 390.10 g/mol
LogP 4.54284
Topological Polar Surface Area 70.5 Ų
Hydrogen Bond Donors 1
Hydrogen Bond Acceptors 5
Rotatable Bonds 4
Exact Mass 390.10382
Heavy Atoms 28
Complexity 1085.2344

Chemical Identifiers

CAS Number 487033-69-2
SMILES CC1=CC=C(C=C1)C2C(=C(C(=O)N2C3=CC=CC(=N3)C)O)C(=O)C4=CC=CS4

Product Overview

3-hydroxy-1-(6-methylpyridin-2-yl)-4-(thiophene-2-carbonyl)-5-(p-tolyl)-1H-pyrrol-2(5H)-one (CAS 487033-69-2), with molecular formula C22H18N2O3S and molecular weight 390.10 g/mol. IUPAC: 4-hydroxy-2-(4-methylphenyl)-1-(6-methyl-2-pyridinyl)-3-(thiophene-2-carbonyl)-2H-pyrrol-5-one.

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Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
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Chemical Property Profile of 3-hydroxy-1-(6-methylpyridin-2-yl)-4-(thiophene-2-carbonyl)-5-(p-tolyl)-1H-pyrrol-2(5H)-one

XLogP
4.54284
TPSA (Topological Polar Surface Area)
70.5
Hydrogen Bond Donors
1
Hydrogen Bond Acceptors
5
Rotatable Bonds
4
Heavy Atoms
28
Complexity
1085.2344
Exact Mass
390.10382
Monoisotopic Mass
390.10382
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of 3-hydroxy-1-(6-methylpyridin-2-yl)-4-(thiophene-2-carbonyl)-5-(p-tolyl)-1H-pyrrol-2(5H)-one

The XLogP value of 4.54284 indicates that 3-hydroxy-1-(6-methylpyridin-2-yl)-4-(thiophene-2-carbonyl)-5-(p-tolyl)-1H-pyrrol-2(5H)-one is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 70.5 Ų falls within the moderate polarity range, balancing permeability and solubility for 3-hydroxy-1-(6-methylpyridin-2-yl)-4-(thiophene-2-carbonyl)-5-(p-tolyl)-1H-pyrrol-2(5H)-one. Following Lipinski's Rule of Five, 3-hydroxy-1-(6-methylpyridin-2-yl)-4-(thiophene-2-carbonyl)-5-(p-tolyl)-1H-pyrrol-2(5H)-one has 1 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of 3-hydroxy-1-(6-methylpyridin-2-yl)-4-(thiophene-2-carbonyl)-5-(p-tolyl)-1H-pyrrol-2(5H)-one?

The CAS number of 3-hydroxy-1-(6-methylpyridin-2-yl)-4-(thiophene-2-carbonyl)-5-(p-tolyl)-1H-pyrrol-2(5H)-one is 487033-69-2.

What is the molecular formula of 3-hydroxy-1-(6-methylpyridin-2-yl)-4-(thiophene-2-carbonyl)-5-(p-tolyl)-1H-pyrrol-2(5H)-one?

The molecular formula of 3-hydroxy-1-(6-methylpyridin-2-yl)-4-(thiophene-2-carbonyl)-5-(p-tolyl)-1H-pyrrol-2(5H)-one is C22H18N2O3S.

What is the molecular weight of 3-hydroxy-1-(6-methylpyridin-2-yl)-4-(thiophene-2-carbonyl)-5-(p-tolyl)-1H-pyrrol-2(5H)-one?

The molecular weight of 3-hydroxy-1-(6-methylpyridin-2-yl)-4-(thiophene-2-carbonyl)-5-(p-tolyl)-1H-pyrrol-2(5H)-one is 390.10 g/mol.

Where can I buy 3-hydroxy-1-(6-methylpyridin-2-yl)-4-(thiophene-2-carbonyl)-5-(p-tolyl)-1H-pyrrol-2(5H)-one?

You can request a quote for 3-hydroxy-1-(6-methylpyridin-2-yl)-4-(thiophene-2-carbonyl)-5-(p-tolyl)-1H-pyrrol-2(5H)-one directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for 3-hydroxy-1-(6-methylpyridin-2-yl)-4-(thiophene-2-carbonyl)-5-(p-tolyl)-1H-pyrrol-2(5H)-one?

Yes, KEHONG BIO provides custom synthesis services for 3-hydroxy-1-(6-methylpyridin-2-yl)-4-(thiophene-2-carbonyl)-5-(p-tolyl)-1H-pyrrol-2(5H)-one and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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