![[4-amino-2-[3-(trifluoromethyl)anilino]-1,3-thiazol-5-yl]-(1,3-benzodioxol-4-yl)methanone structure](/static/products/487/487032-72-4.png)
[4-amino-2-[3-(trifluoromethyl)anilino]-1,3-thiazol-5-yl]-(1,3-benzodioxol-4-yl)methanone
TL;DR: [4-amino-2-[3-(trifluoromethyl)anilino]-1,3-thiazol-5-yl]-(1,3-benzodioxol-4-yl)methanone (CAS 487032-72-4) is a chemical compound with molecular formula C18H12F3N3O3S and molecular weight 407.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
[4-amino-2-[3-(trifluoromethyl)anilino]-1,3-thiazol-5-yl]-(1,3-benzodioxol-4-yl)methanone
Also Known As: [4-amino-2-[3-(trifluoromethyl)anilino]-1,3-thiazol-5-yl]-(1,3-benzodioxol-4-yl)methanone|(4-amino-2-((3-(trifluoromethyl)phenyl)amino)thiazol-5-yl)(benzo[d][1,3]dioxol-4-yl)methanone|(4-amino-2-{[3-(trifluoromethyl)phenyl]amino}-1,3-thiazol-5-yl)(1,3-benzodioxol-4-yl)methanone|2H-benzo[d]1,3-dioxolan-4-yl 4-amino-2-{[3-(trifluoromethyl)phenyl]amino}(1,3- thiazol-5-yl) ketone
| Molecular Formula | C18H12F3N3O3S |
|---|---|
| Molecular Weight | 407.06 g/mol |
| LogP | 4.4474 |
| Topological Polar Surface Area | 86.47 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 4 |
| Exact Mass | 407.05515 |
| Heavy Atoms | 28 |
| Complexity | 1065.7147 |
Chemical Identifiers
| CAS Number | 487032-72-4 |
|---|---|
| SMILES | C1OC2=CC=CC(=C2O1)C(=O)C3=C(N=C(S3)NC4=CC=CC(=C4)C(F)(F)F)N |
Product Overview
[4-amino-2-[3-(trifluoromethyl)anilino]-1,3-thiazol-5-yl]-(1,3-benzodioxol-4-yl)methanone (CAS 487032-72-4), with molecular formula C18H12F3N3O3S and molecular weight 407.06 g/mol. IUPAC: [4-amino-2-[3-(trifluoromethyl)anilino]-1,3-thiazol-5-yl]-(1,3-benzodioxol-4-yl)methanone.
Chemical Property Profile of [4-amino-2-[3-(trifluoromethyl)anilino]-1,3-thiazol-5-yl]-(1,3-benzodioxol-4-yl)methanone
Property Insights of [4-amino-2-[3-(trifluoromethyl)anilino]-1,3-thiazol-5-yl]-(1,3-benzodioxol-4-yl)methanone
The XLogP value of 4.4474 indicates that [4-amino-2-[3-(trifluoromethyl)anilino]-1,3-thiazol-5-yl]-(1,3-benzodioxol-4-yl)methanone is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 86.47 Ų falls within the moderate polarity range, balancing permeability and solubility for [4-amino-2-[3-(trifluoromethyl)anilino]-1,3-thiazol-5-yl]-(1,3-benzodioxol-4-yl)methanone. Following Lipinski's Rule of Five, [4-amino-2-[3-(trifluoromethyl)anilino]-1,3-thiazol-5-yl]-(1,3-benzodioxol-4-yl)methanone has 2 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of [4-amino-2-[3-(trifluoromethyl)anilino]-1,3-thiazol-5-yl]-(1,3-benzodioxol-4-yl)methanone?
The CAS number of [4-amino-2-[3-(trifluoromethyl)anilino]-1,3-thiazol-5-yl]-(1,3-benzodioxol-4-yl)methanone is 487032-72-4.
What is the molecular formula of [4-amino-2-[3-(trifluoromethyl)anilino]-1,3-thiazol-5-yl]-(1,3-benzodioxol-4-yl)methanone?
The molecular formula of [4-amino-2-[3-(trifluoromethyl)anilino]-1,3-thiazol-5-yl]-(1,3-benzodioxol-4-yl)methanone is C18H12F3N3O3S.
What is the molecular weight of [4-amino-2-[3-(trifluoromethyl)anilino]-1,3-thiazol-5-yl]-(1,3-benzodioxol-4-yl)methanone?
The molecular weight of [4-amino-2-[3-(trifluoromethyl)anilino]-1,3-thiazol-5-yl]-(1,3-benzodioxol-4-yl)methanone is 407.06 g/mol.
Where can I buy [4-amino-2-[3-(trifluoromethyl)anilino]-1,3-thiazol-5-yl]-(1,3-benzodioxol-4-yl)methanone?
You can request a quote for [4-amino-2-[3-(trifluoromethyl)anilino]-1,3-thiazol-5-yl]-(1,3-benzodioxol-4-yl)methanone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for [4-amino-2-[3-(trifluoromethyl)anilino]-1,3-thiazol-5-yl]-(1,3-benzodioxol-4-yl)methanone?
Yes, KEHONG BIO provides custom synthesis services for [4-amino-2-[3-(trifluoromethyl)anilino]-1,3-thiazol-5-yl]-(1,3-benzodioxol-4-yl)methanone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.