(E)-N-(2-(1-cyano-2-(4-isopropylphenyl)vinyl)-4-(p-tolyl)thiazol-5-yl)acetamide
TL;DR: (E)-N-(2-(1-cyano-2-(4-isopropylphenyl)vinyl)-4-(p-tolyl)thiazol-5-yl)acetamide (CAS 487019-54-5) is a chemical compound with molecular formula C24H23N3OS and molecular weight 401.16 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[2-[(E)-1-cyano-2-(4-propan-2-ylphenyl)ethenyl]-4-(4-methylphenyl)-1,3-thiazol-5-yl]acetamide
Also Known As: (E)-N-(2-(1-cyano-2-(4-isopropylphenyl)vinyl)-4-(p-tolyl)thiazol-5-yl)acetamide, N-[2-[(E)-1-cyano-2-(4-propan-2-ylphenyl)ethenyl]-4-(4-methylphenyl)-1,3-thiazol-5-yl]acetamide, N-[2-{(E)-1-cyano-2-[4-(propan-2-yl)phenyl]ethenyl}-4-(4-methylphenyl)-1,3-thiazol-5-yl]acetamide
| Molecular Formula | C24H23N3OS |
|---|---|
| Molecular Weight | 401.16 g/mol |
| LogP | 6.2645 |
| Topological Polar Surface Area | 65.78 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 5 |
| Exact Mass | 401.1562 |
| Heavy Atoms | 29 |
| Complexity | 1084.6497 |
Chemical Identifiers
| CAS Number | 487019-54-5 |
|---|---|
| SMILES | CC1=CC=C(C=C1)C2=C(SC(=N2)/C(=C/C3=CC=C(C=C3)C(C)C)/C#N)NC(=O)C |
Product Overview
(E)-N-(2-(1-cyano-2-(4-isopropylphenyl)vinyl)-4-(p-tolyl)thiazol-5-yl)acetamide (CAS 487019-54-5), with molecular formula C24H23N3OS and molecular weight 401.16 g/mol. IUPAC: N-[2-[(E)-1-cyano-2-(4-propan-2-ylphenyl)ethenyl]-4-(4-methylphenyl)-1,3-thiazol-5-yl]acetamide.
Chemical Property Profile of (E)-N-(2-(1-cyano-2-(4-isopropylphenyl)vinyl)-4-(p-tolyl)thiazol-5-yl)acetamide
Property Insights of (E)-N-(2-(1-cyano-2-(4-isopropylphenyl)vinyl)-4-(p-tolyl)thiazol-5-yl)acetamide
The XLogP value of 6.2645 indicates that (E)-N-(2-(1-cyano-2-(4-isopropylphenyl)vinyl)-4-(p-tolyl)thiazol-5-yl)acetamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 65.78 Ų falls within the moderate polarity range, balancing permeability and solubility for (E)-N-(2-(1-cyano-2-(4-isopropylphenyl)vinyl)-4-(p-tolyl)thiazol-5-yl)acetamide. Following Lipinski's Rule of Five, (E)-N-(2-(1-cyano-2-(4-isopropylphenyl)vinyl)-4-(p-tolyl)thiazol-5-yl)acetamide has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), which may warrant consideration for formulation optimization.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of (E)-N-(2-(1-cyano-2-(4-isopropylphenyl)vinyl)-4-(p-tolyl)thiazol-5-yl)acetamide?
The CAS number of (E)-N-(2-(1-cyano-2-(4-isopropylphenyl)vinyl)-4-(p-tolyl)thiazol-5-yl)acetamide is 487019-54-5.
What is the molecular formula of (E)-N-(2-(1-cyano-2-(4-isopropylphenyl)vinyl)-4-(p-tolyl)thiazol-5-yl)acetamide?
The molecular formula of (E)-N-(2-(1-cyano-2-(4-isopropylphenyl)vinyl)-4-(p-tolyl)thiazol-5-yl)acetamide is C24H23N3OS.
What is the molecular weight of (E)-N-(2-(1-cyano-2-(4-isopropylphenyl)vinyl)-4-(p-tolyl)thiazol-5-yl)acetamide?
The molecular weight of (E)-N-(2-(1-cyano-2-(4-isopropylphenyl)vinyl)-4-(p-tolyl)thiazol-5-yl)acetamide is 401.16 g/mol.
Where can I buy (E)-N-(2-(1-cyano-2-(4-isopropylphenyl)vinyl)-4-(p-tolyl)thiazol-5-yl)acetamide?
You can request a quote for (E)-N-(2-(1-cyano-2-(4-isopropylphenyl)vinyl)-4-(p-tolyl)thiazol-5-yl)acetamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for (E)-N-(2-(1-cyano-2-(4-isopropylphenyl)vinyl)-4-(p-tolyl)thiazol-5-yl)acetamide?
Yes, KEHONG BIO provides custom synthesis services for (E)-N-(2-(1-cyano-2-(4-isopropylphenyl)vinyl)-4-(p-tolyl)thiazol-5-yl)acetamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.