NRP1 antagonist 2
TL;DR: NRP1 antagonist 2 (CAS 483289-96-9) is a chemical compound with molecular formula C20H17ClN6OS2 and molecular weight 456.06 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[[4-(3-chlorophenyl)-5-phenyl-1,2,4-triazol-3-yl]sulfanyl]-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide
Also Known As: NRP1 antagonist 2, BAS 02750457, 2-[[4-(3-chlorophenyl)-5-phenyl-1,2,4-triazol-3-yl]sulfanyl]-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide, 2-[4-(3-chlorophenyl)-5-phenyl(1,2,4-triazol-3-ylthio)]-N-(5-ethyl(1,3,4-thiad iazol-2-yl))acetamide, 2-{[4-(3-chlorophenyl)-5-phenyl-4H-1,2,4-triazol-3-yl]sulfanyl}-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide
| Molecular Formula | C20H17ClN6OS2 |
|---|---|
| Molecular Weight | 456.06 g/mol |
| LogP | 4.7324 |
| Topological Polar Surface Area | 85.59 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 7 |
| Rotatable Bonds | 7 |
| Exact Mass | 456.0594 |
| Heavy Atoms | 30 |
| Complexity | 1161.0853 |
Chemical Identifiers
| CAS Number | 483289-96-9 |
|---|---|
| SMILES | CCC1=NN=C(S1)NC(=O)CSC2=NN=C(N2C3=CC(=CC=C3)Cl)C4=CC=CC=C4 |
Product Overview
NRP1 antagonist 2 (CAS 483289-96-9), with molecular formula C20H17ClN6OS2 and molecular weight 456.06 g/mol. IUPAC: 2-[[4-(3-chlorophenyl)-5-phenyl-1,2,4-triazol-3-yl]sulfanyl]-N-(5-ethyl-1,3,4-thiadiazol-2-yl)acetamide.
Chemical Property Profile of NRP1 antagonist 2
Property Insights of NRP1 antagonist 2
The XLogP value of 4.7324 indicates that NRP1 antagonist 2 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 85.59 Ų falls within the moderate polarity range, balancing permeability and solubility for NRP1 antagonist 2. Following Lipinski's Rule of Five, NRP1 antagonist 2 has 1 hydrogen bond donor(s) and 7 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of NRP1 antagonist 2?
The CAS number of NRP1 antagonist 2 is 483289-96-9.
What is the molecular formula of NRP1 antagonist 2?
The molecular formula of NRP1 antagonist 2 is C20H17ClN6OS2.
What is the molecular weight of NRP1 antagonist 2?
The molecular weight of NRP1 antagonist 2 is 456.06 g/mol.
Where can I buy NRP1 antagonist 2?
You can request a quote for NRP1 antagonist 2 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for NRP1 antagonist 2?
Yes, KEHONG BIO provides custom synthesis services for NRP1 antagonist 2 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.