Tetrahydroprotoberberine
TL;DR: Tetrahydroprotoberberine (CAS 483-49-8) is a chemical compound with molecular formula C17H17N and molecular weight 235.14 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline
Also Known As: Berbine, Tetrahydroprotoberberine, (-)-Berbine, BERBIN, BERBINE [MI]
| Molecular Formula | C17H17N |
|---|---|
| Molecular Weight | 235.14 g/mol |
| LogP | 3.4 |
| Topological Polar Surface Area | 3.2 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 1 |
| Rotatable Bonds | 0 |
| Exact Mass | 235.1361 |
| Heavy Atoms | 18 |
| Complexity | 300.0 |
Chemical Identifiers
| CAS Number | 483-49-8 |
|---|---|
| SMILES | C1CN2CC3=CC=CC=C3CC2C4=CC=CC=C41 |
| InChIKey | BRLDZKPJJNASGG-UHFFFAOYSA-N |
Patent-Derived Application Labels
Derived from 6 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Tetrahydroprotoberberine (CAS 483-49-8), with molecular formula C17H17N and molecular weight 235.14 g/mol. IUPAC: 6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline.
Chemical Property Profile of Tetrahydroprotoberberine
Property Insights of Tetrahydroprotoberberine
The XLogP value of 3.4 indicates that Tetrahydroprotoberberine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 3.2 Ų, Tetrahydroprotoberberine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Tetrahydroprotoberberine has 0 hydrogen bond donor(s) and 1 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Tetrahydroprotoberberine?
The CAS number of Tetrahydroprotoberberine is 483-49-8.
What is the molecular formula of Tetrahydroprotoberberine?
The molecular formula of Tetrahydroprotoberberine is C17H17N.
What is the molecular weight of Tetrahydroprotoberberine?
The molecular weight of Tetrahydroprotoberberine is 235.14 g/mol.
Where can I buy Tetrahydroprotoberberine?
You can request a quote for Tetrahydroprotoberberine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Tetrahydroprotoberberine?
Yes, KEHONG BIO provides custom synthesis services for Tetrahydroprotoberberine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.