Clocortolone
TL;DR: Clocortolone (CAS 4828-27-7) is a chemical compound with molecular formula C22H28ClFO4 and molecular weight 410.17 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(6S,8S,9R,10S,11S,13S,14S,16R,17S)-9-chloro-6-fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-7,8,11,12,14,15,16,17-octahydro-6H-cyclopenta[a]phenanthren-3-one
Also Known As: CLOCORTOLONE, Clocortolona, Clocortolonum, Clorcortelone, Clocortolon
| Molecular Formula | C22H28ClFO4 |
|---|---|
| Molecular Weight | 410.17 g/mol |
| LogP | 2.9981 |
| Topological Polar Surface Area | 74.6 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 2 |
| Exact Mass | 410.16602 |
| Heavy Atoms | 28 |
| Complexity | 793.40625 |
Chemical Identifiers
| CAS Number | 4828-27-7 |
|---|---|
| SMILES | C[C@@H]1C[C@H]2[C@@H]3C[C@@H](C4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@H]1C(=O)CO)C)O)Cl)C)F |
Product Overview
Clocortolone (CAS 4828-27-7), with molecular formula C22H28ClFO4 and molecular weight 410.17 g/mol. IUPAC: (6S,8S,9R,10S,11S,13S,14S,16R,17S)-9-chloro-6-fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-7,8,11,12,14,15,16,17-octahydro-6H-cyclopenta[a]phenanthren-3-one.
Chemical Property Profile of Clocortolone
Property Insights of Clocortolone
The XLogP value of 2.9981 suggests moderate lipophilicity, balancing water solubility and membrane permeability for Clocortolone. The TPSA of 74.6 Ų falls within the moderate polarity range, balancing permeability and solubility for Clocortolone. Following Lipinski's Rule of Five, Clocortolone has 2 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Clocortolone?
The CAS number of Clocortolone is 4828-27-7.
What is the molecular formula of Clocortolone?
The molecular formula of Clocortolone is C22H28ClFO4.
What is the molecular weight of Clocortolone?
The molecular weight of Clocortolone is 410.17 g/mol.
Where can I buy Clocortolone?
You can request a quote for Clocortolone directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Clocortolone?
Yes, KEHONG BIO provides custom synthesis services for Clocortolone and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.