N-(4-chloro-2-methoxy-5-methylphenyl)-2-cyano-3-(thiophen-2-yl)prop-2-enamide
TL;DR: N-(4-chloro-2-methoxy-5-methylphenyl)-2-cyano-3-(thiophen-2-yl)prop-2-enamide (CAS 482587-96-2) is a chemical compound with molecular formula C16H13ClN2O2S and molecular weight 332.04 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(E)-N-(4-chloro-2-methoxy-5-methylphenyl)-2-cyano-3-thiophen-2-ylprop-2-enamide
Also Known As: N-(4-chloro-2-methoxy-5-methylphenyl)-2-cyano-3-(thiophen-2-yl)prop-2-enamide, (E)-N-(4-chloro-2-methoxy-5-methylphenyl)-2-cyano-3-thiophen-2-ylprop-2-enamide
| Molecular Formula | C16H13ClN2O2S |
|---|---|
| Molecular Weight | 332.04 g/mol |
| LogP | 4.2642 |
| Topological Polar Surface Area | 62.12 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 4 |
| Rotatable Bonds | 4 |
| Exact Mass | 332.03864 |
| Heavy Atoms | 22 |
| Complexity | 761.19324 |
Chemical Identifiers
| CAS Number | 482587-96-2 |
|---|---|
| SMILES | CC1=CC(=C(C=C1Cl)OC)NC(=O)/C(=C/C2=CC=CS2)/C#N |
Product Overview
N-(4-chloro-2-methoxy-5-methylphenyl)-2-cyano-3-(thiophen-2-yl)prop-2-enamide (CAS 482587-96-2), with molecular formula C16H13ClN2O2S and molecular weight 332.04 g/mol. IUPAC: (E)-N-(4-chloro-2-methoxy-5-methylphenyl)-2-cyano-3-thiophen-2-ylprop-2-enamide.
Chemical Property Profile of N-(4-chloro-2-methoxy-5-methylphenyl)-2-cyano-3-(thiophen-2-yl)prop-2-enamide
Property Insights of N-(4-chloro-2-methoxy-5-methylphenyl)-2-cyano-3-(thiophen-2-yl)prop-2-enamide
The XLogP value of 4.2642 indicates that N-(4-chloro-2-methoxy-5-methylphenyl)-2-cyano-3-(thiophen-2-yl)prop-2-enamide is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 62.12 Ų falls within the moderate polarity range, balancing permeability and solubility for N-(4-chloro-2-methoxy-5-methylphenyl)-2-cyano-3-(thiophen-2-yl)prop-2-enamide. Following Lipinski's Rule of Five, N-(4-chloro-2-methoxy-5-methylphenyl)-2-cyano-3-(thiophen-2-yl)prop-2-enamide has 1 hydrogen bond donor(s) and 4 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of N-(4-chloro-2-methoxy-5-methylphenyl)-2-cyano-3-(thiophen-2-yl)prop-2-enamide?
The CAS number of N-(4-chloro-2-methoxy-5-methylphenyl)-2-cyano-3-(thiophen-2-yl)prop-2-enamide is 482587-96-2.
What is the molecular formula of N-(4-chloro-2-methoxy-5-methylphenyl)-2-cyano-3-(thiophen-2-yl)prop-2-enamide?
The molecular formula of N-(4-chloro-2-methoxy-5-methylphenyl)-2-cyano-3-(thiophen-2-yl)prop-2-enamide is C16H13ClN2O2S.
What is the molecular weight of N-(4-chloro-2-methoxy-5-methylphenyl)-2-cyano-3-(thiophen-2-yl)prop-2-enamide?
The molecular weight of N-(4-chloro-2-methoxy-5-methylphenyl)-2-cyano-3-(thiophen-2-yl)prop-2-enamide is 332.04 g/mol.
Where can I buy N-(4-chloro-2-methoxy-5-methylphenyl)-2-cyano-3-(thiophen-2-yl)prop-2-enamide?
You can request a quote for N-(4-chloro-2-methoxy-5-methylphenyl)-2-cyano-3-(thiophen-2-yl)prop-2-enamide directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for N-(4-chloro-2-methoxy-5-methylphenyl)-2-cyano-3-(thiophen-2-yl)prop-2-enamide?
Yes, KEHONG BIO provides custom synthesis services for N-(4-chloro-2-methoxy-5-methylphenyl)-2-cyano-3-(thiophen-2-yl)prop-2-enamide and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.