Tylophorine
TL;DR: Tylophorine (CAS 482-20-2) is a chemical compound with molecular formula C24H27NO4 and molecular weight 393.19 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
(13aS)-2,3,6,7-tetramethoxy-9,11,12,13,13a,14-hexahydrophenanthro[9,10-f]indolizine
Also Known As: Tylophorine, Tylophorin, (+)-(S)-Tylophorine, tylophorine(8ci), (+)-Tylophorine
| Molecular Formula | C24H27NO4 |
|---|---|
| Molecular Weight | 393.19 g/mol |
| LogP | 4.7 |
| Topological Polar Surface Area | 40.2 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 393.194 |
| Heavy Atoms | 29 |
| Complexity | 573.0 |
Chemical Identifiers
| CAS Number | 482-20-2 |
|---|---|
| SMILES | COC1=C(C=C2C(=C1)C3=C(CN4CCC[C@H]4C3)C5=CC(=C(C=C52)OC)OC)OC |
| InChIKey | SSEUDFYBEOIWGF-AWEZNQCLSA-N |
Patent-Derived Application Labels
Derived from 5 IPC patent classification(s) across the SureChEMBL global patent database.
Product Overview
Tylophorine (CAS 482-20-2), with molecular formula C24H27NO4 and molecular weight 393.19 g/mol. IUPAC: (13aS)-2,3,6,7-tetramethoxy-9,11,12,13,13a,14-hexahydrophenanthro[9,10-f]indolizine.
Chemical Property Profile of Tylophorine
Property Insights of Tylophorine
The XLogP value of 4.7 indicates that Tylophorine is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 40.2 Ų, Tylophorine exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, Tylophorine has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of Tylophorine?
The CAS number of Tylophorine is 482-20-2.
What is the molecular formula of Tylophorine?
The molecular formula of Tylophorine is C24H27NO4.
What is the molecular weight of Tylophorine?
The molecular weight of Tylophorine is 393.19 g/mol.
Where can I buy Tylophorine?
You can request a quote for Tylophorine directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for Tylophorine?
Yes, KEHONG BIO provides custom synthesis services for Tylophorine and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.