6-(3-Isopropoxy-5-(2-(3-thienyl)ethoxy)benzamido)nicotinic acid
TL;DR: 6-(3-Isopropoxy-5-(2-(3-thienyl)ethoxy)benzamido)nicotinic acid (CAS 480463-02-3) is a chemical compound with molecular formula C22H22N2O5S and molecular weight 426.12 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6-[[3-propan-2-yloxy-5-(2-thiophen-3-ylethoxy)benzoyl]amino]pyridine-3-carboxylic acid
Also Known As: Glucokinase activator 6, J3.324.599H, 6-(3-Isopropoxy-5-(2-(3-thienyl)ethoxy)benzamido)nicotinic acid, 6-[[3-propan-2-yloxy-5-(2-thiophen-3-ylethoxy)benzoyl]amino]pyridine-3-carboxylic Acid, 6-({3-isopropoxy-5-[2-(3-thienyl)ethoxy]benzoyl}amino)nicotinic acid
| Molecular Formula | C22H22N2O5S |
|---|---|
| Molecular Weight | 426.12 g/mol |
| LogP | 4.5023 |
| Topological Polar Surface Area | 97.75 Ų |
| Hydrogen Bond Donors | 2 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 9 |
| Exact Mass | 426.12494 |
| Heavy Atoms | 30 |
| Complexity | 1000.8772 |
Chemical Identifiers
| CAS Number | 480463-02-3 |
|---|---|
| SMILES | CC(C)OC1=CC(=CC(=C1)OCCC2=CSC=C2)C(=O)NC3=NC=C(C=C3)C(=O)O |
Product Overview
6-(3-Isopropoxy-5-(2-(3-thienyl)ethoxy)benzamido)nicotinic acid (CAS 480463-02-3), with molecular formula C22H22N2O5S and molecular weight 426.12 g/mol. IUPAC: 6-[[3-propan-2-yloxy-5-(2-thiophen-3-ylethoxy)benzoyl]amino]pyridine-3-carboxylic acid.
Chemical Property Profile of 6-(3-Isopropoxy-5-(2-(3-thienyl)ethoxy)benzamido)nicotinic acid
Property Insights of 6-(3-Isopropoxy-5-(2-(3-thienyl)ethoxy)benzamido)nicotinic acid
The XLogP value of 4.5023 indicates that 6-(3-Isopropoxy-5-(2-(3-thienyl)ethoxy)benzamido)nicotinic acid is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 97.75 Ų falls within the moderate polarity range, balancing permeability and solubility for 6-(3-Isopropoxy-5-(2-(3-thienyl)ethoxy)benzamido)nicotinic acid. Following Lipinski's Rule of Five, 6-(3-Isopropoxy-5-(2-(3-thienyl)ethoxy)benzamido)nicotinic acid has 2 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 6-(3-Isopropoxy-5-(2-(3-thienyl)ethoxy)benzamido)nicotinic acid?
The CAS number of 6-(3-Isopropoxy-5-(2-(3-thienyl)ethoxy)benzamido)nicotinic acid is 480463-02-3.
What is the molecular formula of 6-(3-Isopropoxy-5-(2-(3-thienyl)ethoxy)benzamido)nicotinic acid?
The molecular formula of 6-(3-Isopropoxy-5-(2-(3-thienyl)ethoxy)benzamido)nicotinic acid is C22H22N2O5S.
What is the molecular weight of 6-(3-Isopropoxy-5-(2-(3-thienyl)ethoxy)benzamido)nicotinic acid?
The molecular weight of 6-(3-Isopropoxy-5-(2-(3-thienyl)ethoxy)benzamido)nicotinic acid is 426.12 g/mol.
Where can I buy 6-(3-Isopropoxy-5-(2-(3-thienyl)ethoxy)benzamido)nicotinic acid?
You can request a quote for 6-(3-Isopropoxy-5-(2-(3-thienyl)ethoxy)benzamido)nicotinic acid directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 6-(3-Isopropoxy-5-(2-(3-thienyl)ethoxy)benzamido)nicotinic acid?
Yes, KEHONG BIO provides custom synthesis services for 6-(3-Isopropoxy-5-(2-(3-thienyl)ethoxy)benzamido)nicotinic acid and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.