tert-Butyldimethylsilyl chloroacetate structure

tert-Butyldimethylsilyl chloroacetate

TL;DR: tert-Butyldimethylsilyl chloroacetate (CAS 480439-47-2) is a chemical compound with molecular formula C8H17ClO2Si and molecular weight 208.07 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.

[tert-butyl(dimethyl)silyl] 2-chloroacetate

Also Known As: tert-Butyldimethylsilyl chloroacetate, tert-Butyldimethylsilyl 2-chloroacetate, [tert-butyl(dimethyl)silyl] 2-chloroacetate, Chloroacetic acid, TBDMS derivative, tert-Butyldi(methyl)silyl chloroacetate

CAS: 480439-47-2
Molecular Formula C8H17ClO2Si
Molecular Weight 208.07 g/mol
LogP 2.7736
Topological Polar Surface Area 26.3 Ų
Hydrogen Bond Donors 0
Hydrogen Bond Acceptors 2
Rotatable Bonds 2
Exact Mass 208.06863
Heavy Atoms 12
Complexity 172.3869

Chemical Identifiers

CAS Number 480439-47-2
SMILES CC(C)(C)[Si](C)(C)OC(=O)CCl

Product Overview

tert-Butyldimethylsilyl chloroacetate (CAS 480439-47-2), with molecular formula C8H17ClO2Si and molecular weight 208.07 g/mol. IUPAC: [tert-butyl(dimethyl)silyl] 2-chloroacetate.

🧪
Safety Data Sheet (MSDS / SDS) View the Laboratory Chemical Safety Summary (LCSS) on PubChem — includes GHS classifications, hazard statements, first aid measures, and handling precautions.
View MSDS →

Chemical Property Profile of tert-Butyldimethylsilyl chloroacetate

XLogP
2.7736
TPSA (Topological Polar Surface Area)
26.3
Hydrogen Bond Donors
0
Hydrogen Bond Acceptors
2
Rotatable Bonds
2
Heavy Atoms
12
Complexity
172.3869
Exact Mass
208.06863
Monoisotopic Mass
208.06863
Data Source: Chemical property values are referenced from PubChem, the world's largest open chemistry database maintained by the National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine.

Property Insights of tert-Butyldimethylsilyl chloroacetate

The XLogP value of 2.7736 suggests moderate lipophilicity, balancing water solubility and membrane permeability for tert-Butyldimethylsilyl chloroacetate. With a topological polar surface area (TPSA) of 26.3 Ų, tert-Butyldimethylsilyl chloroacetate exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, tert-Butyldimethylsilyl chloroacetate has 0 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.

Frequently Asked Questions

What is the typical lead time for this product?
Lead time typically ranges from 3-7 business days for in-stock items. For larger quantities or custom orders, please contact us for specific lead times.
Can you provide samples for testing?
Yes, we offer sample quantities for quality testing. Please submit an inquiry with your requirements and we will arrange samples accordingly.
What documentation do you provide with the product?
We provide COA (Certificate of Analysis), MSDS (Material Safety Data Sheet), and technical data sheets with each shipment.
Do you ship internationally?
Yes, we ship to most countries worldwide. Shipping costs and delivery times vary by location. Please contact us for specific shipping information.

Frequently Asked Questions

What is the CAS number of tert-Butyldimethylsilyl chloroacetate?

The CAS number of tert-Butyldimethylsilyl chloroacetate is 480439-47-2.

What is the molecular formula of tert-Butyldimethylsilyl chloroacetate?

The molecular formula of tert-Butyldimethylsilyl chloroacetate is C8H17ClO2Si.

What is the molecular weight of tert-Butyldimethylsilyl chloroacetate?

The molecular weight of tert-Butyldimethylsilyl chloroacetate is 208.07 g/mol.

Where can I buy tert-Butyldimethylsilyl chloroacetate?

You can request a quote for tert-Butyldimethylsilyl chloroacetate directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.

Does KEHONG BIO offer custom synthesis for tert-Butyldimethylsilyl chloroacetate?

Yes, KEHONG BIO provides custom synthesis services for tert-Butyldimethylsilyl chloroacetate and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.

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