5-(3-Chlorothiophen-2-yl)-3-(6-methyl-3-pyridinyl)-1,2,4-oxadiazole
TL;DR: 5-(3-Chlorothiophen-2-yl)-3-(6-methyl-3-pyridinyl)-1,2,4-oxadiazole (CAS 478489-11-1) is a chemical compound with molecular formula C12H8ClN3OS and molecular weight 277.01 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
5-(3-chlorothiophen-2-yl)-3-(6-methyl-3-pyridinyl)-1,2,4-oxadiazole
Also Known As: Pyridine, 5-[5-(3-chloro-2-thienyl)-1,2,4-oxadiazol-3-yl]-2-methyl-, 5-[5-(3-chlorothiophen-2-yl)-1,2,4-oxadiazol-3-yl]-2-methyl-pyridine
| Molecular Formula | C12H8ClN3OS |
|---|---|
| Molecular Weight | 277.01 g/mol |
| LogP | 3.82192 |
| Topological Polar Surface Area | 51.81 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 2 |
| Exact Mass | 277.00766 |
| Heavy Atoms | 18 |
| Complexity | 674.7047 |
Chemical Identifiers
| CAS Number | 478489-11-1 |
|---|---|
| SMILES | CC1=NC=C(C=C1)C2=NOC(=N2)C3=C(C=CS3)Cl |
Product Overview
5-(3-Chlorothiophen-2-yl)-3-(6-methyl-3-pyridinyl)-1,2,4-oxadiazole (CAS 478489-11-1), with molecular formula C12H8ClN3OS and molecular weight 277.01 g/mol. IUPAC: 5-(3-chlorothiophen-2-yl)-3-(6-methyl-3-pyridinyl)-1,2,4-oxadiazole.
Chemical Property Profile of 5-(3-Chlorothiophen-2-yl)-3-(6-methyl-3-pyridinyl)-1,2,4-oxadiazole
Property Insights of 5-(3-Chlorothiophen-2-yl)-3-(6-methyl-3-pyridinyl)-1,2,4-oxadiazole
The XLogP value of 3.82192 indicates that 5-(3-Chlorothiophen-2-yl)-3-(6-methyl-3-pyridinyl)-1,2,4-oxadiazole is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 51.81 Ų, 5-(3-Chlorothiophen-2-yl)-3-(6-methyl-3-pyridinyl)-1,2,4-oxadiazole exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 5-(3-Chlorothiophen-2-yl)-3-(6-methyl-3-pyridinyl)-1,2,4-oxadiazole has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 5-(3-Chlorothiophen-2-yl)-3-(6-methyl-3-pyridinyl)-1,2,4-oxadiazole?
The CAS number of 5-(3-Chlorothiophen-2-yl)-3-(6-methyl-3-pyridinyl)-1,2,4-oxadiazole is 478489-11-1.
What is the molecular formula of 5-(3-Chlorothiophen-2-yl)-3-(6-methyl-3-pyridinyl)-1,2,4-oxadiazole?
The molecular formula of 5-(3-Chlorothiophen-2-yl)-3-(6-methyl-3-pyridinyl)-1,2,4-oxadiazole is C12H8ClN3OS.
What is the molecular weight of 5-(3-Chlorothiophen-2-yl)-3-(6-methyl-3-pyridinyl)-1,2,4-oxadiazole?
The molecular weight of 5-(3-Chlorothiophen-2-yl)-3-(6-methyl-3-pyridinyl)-1,2,4-oxadiazole is 277.01 g/mol.
Where can I buy 5-(3-Chlorothiophen-2-yl)-3-(6-methyl-3-pyridinyl)-1,2,4-oxadiazole?
You can request a quote for 5-(3-Chlorothiophen-2-yl)-3-(6-methyl-3-pyridinyl)-1,2,4-oxadiazole directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 5-(3-Chlorothiophen-2-yl)-3-(6-methyl-3-pyridinyl)-1,2,4-oxadiazole?
Yes, KEHONG BIO provides custom synthesis services for 5-(3-Chlorothiophen-2-yl)-3-(6-methyl-3-pyridinyl)-1,2,4-oxadiazole and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.