GSK-3 Inhibitor II
TL;DR: GSK-3 Inhibitor II (CAS 478482-75-6) is a chemical compound with molecular formula C14H10IN3OS and molecular weight 394.96 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
2-[(3-iodophenyl)methylsulfanyl]-5-pyridin-4-yl-1,3,4-oxadiazole
Also Known As: GSK-3 Inhibitor II, GSK-3beta Inhibitor II, GSK3beta Inhibitor II, GSK-3b inhibitor II, GSK3
| Molecular Formula | C14H10IN3OS |
|---|---|
| Molecular Weight | 394.96 g/mol |
| LogP | 4.0285 |
| Topological Polar Surface Area | 51.81 Ų |
| Hydrogen Bond Donors | 0 |
| Hydrogen Bond Acceptors | 5 |
| Rotatable Bonds | 4 |
| Exact Mass | 394.95892 |
| Heavy Atoms | 20 |
| Complexity | 702.40344 |
Chemical Identifiers
| CAS Number | 478482-75-6 |
|---|---|
| SMILES | C1=CC(=CC(=C1)I)CSC2=NN=C(O2)C3=CC=NC=C3 |
Product Overview
GSK-3 Inhibitor II (CAS 478482-75-6), with molecular formula C14H10IN3OS and molecular weight 394.96 g/mol. IUPAC: 2-[(3-iodophenyl)methylsulfanyl]-5-pyridin-4-yl-1,3,4-oxadiazole.
Chemical Property Profile of GSK-3 Inhibitor II
Property Insights of GSK-3 Inhibitor II
The XLogP value of 4.0285 indicates that GSK-3 Inhibitor II is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 51.81 Ų, GSK-3 Inhibitor II exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, GSK-3 Inhibitor II has 0 hydrogen bond donor(s) and 5 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of GSK-3 Inhibitor II?
The CAS number of GSK-3 Inhibitor II is 478482-75-6.
What is the molecular formula of GSK-3 Inhibitor II?
The molecular formula of GSK-3 Inhibitor II is C14H10IN3OS.
What is the molecular weight of GSK-3 Inhibitor II?
The molecular weight of GSK-3 Inhibitor II is 394.96 g/mol.
Where can I buy GSK-3 Inhibitor II?
You can request a quote for GSK-3 Inhibitor II directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for GSK-3 Inhibitor II?
Yes, KEHONG BIO provides custom synthesis services for GSK-3 Inhibitor II and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.