9L-918
TL;DR: 9L-918 (CAS 478262-16-7) is a chemical compound with molecular formula C20H17ClF3N5OS and molecular weight 467.08 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
N-[2-[4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazin-1-yl]-3-pyridinyl]thiophene-2-carboxamide
Also Known As: 9L-918, N-(2-{4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazino}-3-pyridinyl)-2-thiophenecarboxamide, N-(2-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}pyridin-3-yl)thiophene-2-carboxamide, N-[2-[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]pyridin-3-yl]thiophene-2-carboxamide
| Molecular Formula | C20H17ClF3N5OS |
|---|---|
| Molecular Weight | 467.08 g/mol |
| LogP | 4.7892 |
| Topological Polar Surface Area | 61.36 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 6 |
| Rotatable Bonds | 4 |
| Exact Mass | 467.07944 |
| Heavy Atoms | 31 |
| Complexity | 1068.9274 |
Chemical Identifiers
| CAS Number | 478262-16-7 |
|---|---|
| SMILES | C1CN(CCN1C2=C(C=CC=N2)NC(=O)C3=CC=CS3)C4=C(C=C(C=N4)C(F)(F)F)Cl |
Product Overview
9L-918 (CAS 478262-16-7), with molecular formula C20H17ClF3N5OS and molecular weight 467.08 g/mol. IUPAC: N-[2-[4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]piperazin-1-yl]-3-pyridinyl]thiophene-2-carboxamide.
Chemical Property Profile of 9L-918
Property Insights of 9L-918
The XLogP value of 4.7892 indicates that 9L-918 is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. The TPSA of 61.36 Ų falls within the moderate polarity range, balancing permeability and solubility for 9L-918. Following Lipinski's Rule of Five, 9L-918 has 1 hydrogen bond donor(s) and 6 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 9L-918?
The CAS number of 9L-918 is 478262-16-7.
What is the molecular formula of 9L-918?
The molecular formula of 9L-918 is C20H17ClF3N5OS.
What is the molecular weight of 9L-918?
The molecular weight of 9L-918 is 467.08 g/mol.
Where can I buy 9L-918?
You can request a quote for 9L-918 directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 9L-918?
Yes, KEHONG BIO provides custom synthesis services for 9L-918 and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.