6-(3-Bromophenyl)-4-(4-chlorophenyl)-2-hydroxynicotinonitrile
TL;DR: 6-(3-Bromophenyl)-4-(4-chlorophenyl)-2-hydroxynicotinonitrile (CAS 478261-45-9) is a chemical compound with molecular formula C18H10BrClN2O and molecular weight 383.97 g/mol, supplied by Kehong Biological (Henan Kehong Biological Technology Co., Ltd.) with CRO/CDMO custom synthesis services.
6-(3-bromophenyl)-4-(4-chlorophenyl)-2-oxo-1H-pyridine-3-carbonitrile
Also Known As: Bionet1_002660, 9L-368S, 6-(3-bromophenyl)-4-(4-chlorophenyl)-2-hydroxynicotinonitrile, 6-(3-bromophenyl)-4-(4-chlorophenyl)-2-hydroxypyridine-3-carbonitrile, 6-(3-bromophenyl)-4-(4-chlorophenyl)-2-oxo-1H-pyridine-3-carbonitrile
| Molecular Formula | C18H10BrClN2O |
|---|---|
| Molecular Weight | 383.97 g/mol |
| LogP | 4.99648 |
| Topological Polar Surface Area | 56.65 Ų |
| Hydrogen Bond Donors | 1 |
| Hydrogen Bond Acceptors | 2 |
| Rotatable Bonds | 2 |
| Exact Mass | 383.9665 |
| Heavy Atoms | 23 |
| Complexity | 971.5471 |
Chemical Identifiers
| CAS Number | 478261-45-9 |
|---|---|
| SMILES | C1=CC(=CC(=C1)Br)C2=CC(=C(C(=O)N2)C#N)C3=CC=C(C=C3)Cl |
Product Overview
6-(3-Bromophenyl)-4-(4-chlorophenyl)-2-hydroxynicotinonitrile (CAS 478261-45-9), with molecular formula C18H10BrClN2O and molecular weight 383.97 g/mol. IUPAC: 6-(3-bromophenyl)-4-(4-chlorophenyl)-2-oxo-1H-pyridine-3-carbonitrile.
Chemical Property Profile of 6-(3-Bromophenyl)-4-(4-chlorophenyl)-2-hydroxynicotinonitrile
Property Insights of 6-(3-Bromophenyl)-4-(4-chlorophenyl)-2-hydroxynicotinonitrile
The XLogP value of 4.99648 indicates that 6-(3-Bromophenyl)-4-(4-chlorophenyl)-2-hydroxynicotinonitrile is lipophilic (fat-soluble), which may influence its absorption, distribution, and formulation strategy. With a topological polar surface area (TPSA) of 56.65 Ų, 6-(3-Bromophenyl)-4-(4-chlorophenyl)-2-hydroxynicotinonitrile exhibits relatively low polarity, potentially indicating favorable cell membrane permeability. Following Lipinski's Rule of Five, 6-(3-Bromophenyl)-4-(4-chlorophenyl)-2-hydroxynicotinonitrile has 1 hydrogen bond donor(s) and 2 hydrogen bond acceptor(s), all within the drug-like range, suggesting favorable oral bioavailability potential.
Frequently Asked Questions
Frequently Asked Questions
What is the CAS number of 6-(3-Bromophenyl)-4-(4-chlorophenyl)-2-hydroxynicotinonitrile?
The CAS number of 6-(3-Bromophenyl)-4-(4-chlorophenyl)-2-hydroxynicotinonitrile is 478261-45-9.
What is the molecular formula of 6-(3-Bromophenyl)-4-(4-chlorophenyl)-2-hydroxynicotinonitrile?
The molecular formula of 6-(3-Bromophenyl)-4-(4-chlorophenyl)-2-hydroxynicotinonitrile is C18H10BrClN2O.
What is the molecular weight of 6-(3-Bromophenyl)-4-(4-chlorophenyl)-2-hydroxynicotinonitrile?
The molecular weight of 6-(3-Bromophenyl)-4-(4-chlorophenyl)-2-hydroxynicotinonitrile is 383.97 g/mol.
Where can I buy 6-(3-Bromophenyl)-4-(4-chlorophenyl)-2-hydroxynicotinonitrile?
You can request a quote for 6-(3-Bromophenyl)-4-(4-chlorophenyl)-2-hydroxynicotinonitrile directly from KEHONG BIO. Contact us or email info@kehongbio.com for pricing and availability.
Does KEHONG BIO offer custom synthesis for 6-(3-Bromophenyl)-4-(4-chlorophenyl)-2-hydroxynicotinonitrile?
Yes, KEHONG BIO provides custom synthesis services for 6-(3-Bromophenyl)-4-(4-chlorophenyl)-2-hydroxynicotinonitrile and related compounds. Contact us with your specific requirements including quantity, purity, and timeline.